Results 121 to 130 of about 466,984 (264)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The value management cycle as a sustainable HRM framework: insights from Chinese Huawei's practices of value creation, evaluation, and distribution. [PDF]

Front Psychol
Liang R.
europepmc   +1 more source

Early evidence on how Industry 4.0 reshapes MNEs' global value chains: The role of value creation versus value capturing by headquarters and foreign subsidiaries. [PDF]

J Int Bus Stud, 2023
Lee JY, Kim D, Choi B, Jiménez A.
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

The value of lithography in artistic creation

Studiul artelor şi culturologie: istorie, teorie, practică
In the carried out research is highlighted the role and contribution of lithography as an original technique of multiplication, which contributed to the development of graphic art. Focusing on the presentation of the technical characteristics, the author pleads for bringing back the interest of plastic artists and graphic design students towards this ...
openaire   +2 more sources

Unicorns transforming the practice of urology: value creation and allocation in the digital age. [PDF]

World J Urol
Erben P, Rodler S, Turki AT, Witzsch U, Thielscher C.   +4 more
europepmc   +1 more source

Discovering the Value Creation System in IoT Ecosystems. [PDF]

Sensors (Basel), 2021
Lopez CA, Castillo LF, Corchado JM.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The data-driven decision-making, sustainable value creation, and international firm performance: Micro-level evidence based on AI language models. [PDF]

PLoS One
Xu M, Lu B.
europepmc   +1 more source

Innovating agri-food business models after the Covid-19 pandemic: The impact of digital technologies on the value creation and value capture mechanisms. [PDF]

Technol Forecast Soc Change, 2023
Mancuso I, Messeni Petruzzelli A, Panniello U.   +2 more
europepmc   +1 more source