Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
The potential of shared value creation: a theoretical analysis
Romanian Economic Journal, 2016 The urgent issues economy, environment and society are facing need new approaches which allow a well-balanced sharing of value created by the economy. A step forward is the concept of shared value creation.
Victor Danciu
doaj
What's in it for me? A mixed-methods study on teachers' value creation in an inter-institutional community on open educational resources in higher education. [PDF]
Educ Inf Technol (Dordr), 2023 Baas M +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Toward Economic Growth and Value Creation Through Social Entrepreneurship: Modelling the Mediating Role of Innovation. [PDF]
Front Psychol, 2022 Wang W.
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The value management cycle as a sustainable HRM framework: insights from Chinese Huawei's practices of value creation, evaluation, and distribution. [PDF]
Front PsycholLiang R.
europepmc +1 more source
Discovering the Value Creation System in IoT Ecosystems. [PDF]
Sensors (Basel), 2021 Lopez CA, Castillo LF, Corchado JM.
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
From Value Creation to Sustainability: Exploring the Mediating Effect of Acculturative Isolating Product Advantage in Samarinda's Iconic Textile Industry. [PDF]
F1000ResAprianti DI +4 more
europepmc +1 more source