Results 51 to 60 of about 16,831,339 (309)

Spatial‐hindrance‐based pro‐Adalimumab prevents anti‐idiotypic antibody interference in pharmacokinetic and therapeutic efficacy

Bioengineering & Translational Medicine
Adalimumab (Humira) represents a major advance in rheumatoid arthritis (RA) therapy. However, with long‐term administration of Adalimumab, anti‐idiotypic antibody (anti‐Id Ab) accelerates the Adalimumab clearance rate and reduces the therapeutic effect ...
Bo‐Cheng Huang, Yu‐Tung Chen, Yun‐Chi Lu, Kai‐Wen Ho, Shih‐Ting Hong, Tzu‐Yi Liao, I‐Hsuan Wu, En‐Shuo Liu, Jun‐Min Liao, Fang‐Ming Chen, Chia‐Ching Li, Chih‐Hung Chuang, Chiao‐Yun Chen, Tian‐Lu Cheng   +13 more
doaj   +1 more source

A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage

Cancer Cell International, 2023
Background The development of nonapoptotic programmed cell death inducers as anticancer agents has emerged as a cancer therapy field. Ferroptosis, ferrous ion-driven programmed cell death that is induced by redox imbalance and dysfunctional reactive ...
Yung-Ding Bow, Ching-Chung Ko, Wen-Tsan Chang, Sih-Yan Chou, Chun-Tzu Hung, Jau-Ling Huang, Chih-Hua Tseng, Yeh-Long Chen, Ruei-Nian Li, Chien-Chih Chiu   +9 more
doaj   +1 more source

Customer value creation in financial services [PDF]

, 2001
Customer value creation is allegedly at the centre of relationships between service recipients and service providers (such as financial service organisations in general, and commercial banks in particular).
Bátiz-Lazo, Bernardo
core  

Intraocular Pressure Measurement with Pneumatonometry and a Tonometer Tip Cover

Ophthalmology and Therapy, 2020
Purpose To investigate the precision and accuracy of IOP measurements using a pneumatonometer and a tonometer tip cover (Tono-Pen® tip cover) acting as a membrane between a cadaver eye model and pneumatonometer probe.
Tanner J. Ferguson, Catherine G. Knier, Uttio Roy Chowdhury, Kjerseten J. Monson, Michael Greenwood, Russell J. Swan, Richard Gorham, John P. Berdahl, Michael P. Fautsch   +8 more
doaj   +1 more source

Digital sustainable entrepreneurship: A business model perspective on embedding digital technologies for social and environmental value creation

Journal of Cleaner Production, 2020
This article explores how sustainable entrepreneurs embed digital technologies in their business models to leverage social and environmental value creation. To this end, we draw on the institutional logics perspective of sustainable business models.
P. Gregori, Patrick Holzmann
semanticscholar   +1 more source

Integrated Value Creation

, 2023
AbstractChapter 1 gave us a clear starting point: responsible companies create integrated value based on financial value (FV), social value (SV), and environmental value (EV). But what does that mean and imply? This chapter outlines what value creation is, and how the various types of value creation can be prioritised. For the alignment of all types of
Dirk Schoenmaker, Willem Schramade
openaire   +1 more source

To generate functional anti-protease-activated receptor-4 (PAR4), a G protein-coupled receptor, antibodies through PAR4-mRNA-LNP immunization

npj Vaccines
G protein-coupled receptors (GPCRs) are key therapeutic targets for various diseases, such as the thrombin receptor protease-activated receptor 4 (PAR4) involved in thrombotic cardiovascular disorders.
En-Shuo Liu, Kai-Wen Ho, Chin-Chung Wu, Hsiao-Li Fan, Ting-Yu Wang, Yuan-Chin Hsieh, Bo-Cheng Huang, Shih-Ting Hong, Tzu-Yi Liao, Yen-Ling Liu, Yu-Tung Chen, Chia-Ching Lee, Chiao-Yun Chen, Chih-Lung Lin, Tian-Lu Cheng   +14 more
doaj   +1 more source

Temperature Driven Current–Voltage Characteristics of Ionic Liquid Type Intelligent Connection Device

IEEE Journal of the Electron Devices Society, 2022
The temperature dependence of an intelligent connection (IConnect) device, in which an ionic liquid (IL) plays an essential role in a memristive function is presented in this study.
Masakazu Kobayashi, Yasumitsu Orii, Hisashi Shima, Yasuhisa Naitoh, Hiroyuki Akinaga, Dan Sato, Takuma Matsuo, Kentaro Kinoshita, Toshiki Nokami, Toshiyuki Itoh   +9 more
doaj   +1 more source

STAKEHOLDER GOVERNANCE: SOLVING THE COLLECTIVE ACTION PROBLEMS IN JOINT VALUE CREATION

Academy of Management Review, 2020
Capitalism works when actors are motivated to engage in joint value creation. Stakeholder theorists have long argued that this is most likely when firms “manage for stakeholders”, but have only rec...
Flore Bridoux, J. Stoelhorst
semanticscholar   +1 more source

Value Creation along a Production-Service Value Chain

International Journal of Engineering and Management Sciences, 2022
Today’s products and services are so complicated and intertwined that their individual value creation is hard to determine. It is especially true when the products and services are necessary complements of each other and when they are affecting customer
Teréz Gerse-Krizsa, Noémi Kalló
doaj   +1 more source