Results 101 to 110 of about 14,679,274 (316)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
General Education at Effat University: A Value-Based Liberal Arts Teaching Model
, 2019 At the core of this teaching model lies a fully dedicated program consciously called the General Education Program (GEP). The technical and social feasibility of GEP, as well as its inherent regard for diversity, are evident in its gradual but persistent
Kaj-Itani, Khadija, Khalid, Mohammad
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
, 1960 1960 and 1964 editions were issued by State Board for Vocational ...
Kansas. Division of Vocational Education
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What makes a successful student teacher in a teacher education program? [PDF]
, 2003 v, 68 leaves ; 29 cm. --The purpose of this project was to explore and investigate specific factors, qualities, and characteristics student teachers and teacher associates believe create teaching success in the classroom during a teacher education ...
Platt, Shari +1 more
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Nature CommunicationsRevealing the surface structure evolution under working conditions is crucial for understanding the activity and stability of electrocatalysts. Platinum, the state-of-the-art electrocatalyst for hydrogen oxidation in fuel cells or hydrogen evolution in ...
Liang Chang +8 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Estimating the Social Value of Higher Education: Willingness to Pay for Community and Technical Colleges [PDF]
Much is known about private returns to education in the form of higher earnings. Less is known about social value, over and above the private, market value.
Blomquist, Glenn C. +4 more
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