Results 121 to 130 of about 6,140,713 (314)
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Cucumber disease detection under complex agricultural conditions faces significant challenges due to multi-scale variation, background clutter, and hardware limitations. This study proposes YOLO-Cucumber, an improved lightweight detection algorithm based
Jun Liu +4 more
doaj +1 more source
Gaining the Arts Advantage: More Lessons from School Districts that Value Arts Education [PDF]
A report from an October 2000 meeting in which 32 school districts from 19 states discussed the current status of arts education in their districts.
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
The Pd (II) Reduction Mechanisms in Bacillus megaterium Y-4 Revealed by Proteomic Analysis
Many studies have been conducted on the microbial reduction of Pd (II) to palladium nanoparticles (Pd-NPs) due to the environmental friendliness, low cost, and the decreased toxicity of Pd (II) ions.
Yuan Chen +6 more
doaj +1 more source
Macroeconomic Instability, Migration, and the Option Value of Education [PDF]
We explore the relation between variability in the rate of return to human capital and investment in education in the context of migration. Specifically, we show that if migration is a possibility, such variability in the rate of return to human capital ...
Eliakim Katz, Hillel Rapoport
core
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Hard carbon is regarded as a promising anode candidate for sodium‐ion batteries due to its low cost, relatively low working voltage, and satisfactory specific capacity.
Jingqiang Zheng +8 more
doaj +1 more source
Measuring the Delivery Costs of Prepurchase Homeownership Education and Counseling [PDF]
In order to understand the roles that public policy and the business and consumer sectors play in paying for homeownership education and counseling, the costs, benefits and beneficiaries of the education and training must be fully accounted for.
Christi Baker, Michael Collins
core
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source

