Results 81 to 90 of about 4,902,162 (302)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
In the Effect of Value Engineering on Organizational Performance (Case study: Water and Wastewater Administration of West Azerbaijan Province) [PDF]
مدیریت بهره وری, 2013 The main objective of this study is to investigate value engineering and its impact on the dimensions of organizational performance in the Water and Wastewater Administration of West Azerbaijan Province and present guidelines for the successful ...
Farhad Nejhad irani +2 more
doaj
Innovation and value-driven engineering [PDF]
Nature Reviews Drug Discovery, 2012 Emerging strategies to simultaneously catalyse rewardable innovation in the field of medical devices and reduce health-care costs could also be applicable in drug development.
openaire +2 more sources
Motion of cranes of bridge type simulation in the MS Excel environment [PDF]
, 2014 The idle times of the crane caused by need of replacement of wheels, can have critical value for functioning of a logistic chain. In article the task about the movement of the crane with a skew with the accounting of several mutually influencing ...
Grigorov, Otto, Stepochkina, Olga
core
Lignin engineering in forest trees [PDF]
, 2019 Wood is a renewable resource that is mainly composed of lignin and cell wall polysaccharides. The polysaccharide fraction is valuable as it can be converted into pulp and paper, or into fermentable sugars.
Alvarenga Chanoca, Alexandra +2 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Investigating Factors Affecting Cost Management Including Target-based Costing and Value Engineering in Tabriz Iran Khodro Industrial Group [PDF]
مدیریت بهره وری, 2013 The aim of the present research is to design the algorithm of the cost management of a business entity in Tabriz Iran Khodro Industrial Group, and it involves the integration of the two methods of target based costing and value engineering.
Mohammadali nejhad Sarokalaye +2 more
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
BuildingsThe slab system can account for a substantial portion of the structural cost; an optimized choice is essential for the financial success of a project.
Ahmet Hicazi +5 more
doaj +1 more source