Results 71 to 80 of about 3,808,413 (255)

Aplikasi Value Engineering untuk Optimalisasi Pembiayaan pada Proyek Pembangunan Gedung Kuliah II UIN Suska Riau

open access: yesJurnal Teknik, 2019
Dalam pembangunan proyek konstruksi sering terjadi penggunaan biaya yang tidak efisien. Pada pembangunan Gedung Kuliah II UIN Suska Riau membutuhkan biaya sebesar Rp. 15.279.840.000 atau Rp. 6.366.600/m2.
Sapitri, Dimas Priambudhi, Elizar
doaj   +1 more source

Value Engineering untuk Bangunan Gudang [PDF]

open access: yes, 2015
Value engineering sangat diperlukan dalam perencanaan proyek karena seringkali terdapat biaya yang tidak diperlukan terdapat dalam perencanaan proyek.
Paryati, N. (Ninik)
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Innovative approach in the stabilisation of coastal slopes [PDF]

open access: yes, 2018
Coastal slope instability poses a risk to life and material properties and is of great concern in times of climate change, posing challenges as communities seek to adapt and ensure resilience.
Mickovski, Slobodan B.   +1 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

OPTIMIZATION OF LIGHTWEIGHT ELECTRIC BUS FRAME DESIGN THROUGH VALUE ENGINEERING APPROACH: A SYSTEMATIC REVIEW AND PARAMETRIC FEASIBILITY ANALYSIS

open access: yesRekayasa Mesin
Lightweight frame design plays a critical role in improving the efficiency and sustainability of electric buses. This study aims to explore the optimization of electric bus frame design through the application of Value Engineering (VE), using a ...
I Nyoman Artana   +3 more
doaj   +1 more source

Space activities in Glasgow; advanced microspacecraft from Scotland [PDF]

open access: yes, 2008
The City of Glasgow is renowned for its engineering and technological innovation; famous Glaswegian inventors and academics include James Watt (Steam Engine) and John Logie Baird (television), amongst many others.
,, Clark, C., McInnes, C., Radice, G.
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Integrated Risk Assessment in Construction Contracts: Comparative Evaluation of Risk Matrix and Monte Carlo Simulation on a High-Rise Office Building Project

open access: yesApplied Sciences
This study investigates the application of two complementary risk analysis methods—risk matrix and Monte Carlo simulation—in the context of a large-scale office building construction project.
Anna Starczyk-Kołbyk, Izabela Jędras
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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