Results 111 to 120 of about 7,419,285 (306)
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
CAPITALIZATION OF RELATIONS IN THE CONTEXT OF VALUE MANAGEMENT
Вестник университета, 2019 The article deals with the capitalization of relations as a result of the interaction under conditions of value management. The author proves that, at the present time to obtain high results organizations form capital, contributing to sustainable socio ...
G. Serebryakova
doaj
Best Practices in Incentive Compensation from the Perspective of Value-based Management [PDF]
As a consequence of the recent global financial crisis, the current economic environment emphasized the weak correlation between company performance and the incentives received by the management staff.
Costin Ciora, Eduard Mădălin Dinu
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The Impact of the Components of Intellectual Capital on the Dimensions of Financial Performance [PDF]
حسابداری دولتی, 2015 This research aims to study the impact of the components of intellectual capital on the dimensions of financial performance in the governmental companies related to the power ministry in Hamedan city.
Mahdi Mahdavikhou +2 more
doaj
Value–based management : shareholder value creation and management
, 2010 Thesis (M.B.A.)--North-West University, Vaal Triangle Campus, 2010. The objective of this study is to evaluate the value drivers that drive the value of companies, as reflected in the share-prices. Through this study, the aim is to draw conclusions on the aspects that drive the share-price of companies.
openaire +2 more sources
Lean knowledge management : the problem of value [PDF]
, 2010 Lean knowledge management is defined here as: getting the right information, in the right form, to the right people at the right time. This definition highlights series of practical problems for knowledge management in the built environment which, in ...
Codinhoto, R +4 more
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Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source