Results 251 to 260 of about 8,676,945 (352)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Deriving monetary value of quality-adjusted life years through life extension from the value of a statistical life. [PDF]

Sci Rep
Tanizawa Y, Ito K, Takashima R.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Oral Health Status and Oral Health-related Quality of Life among Children Born Preterm: A Cross-sectional Study. [PDF]

Int J Clin Pediatr Dent
Devraj IM, Girish MS, Sushma K, Dutta B, Dhull KS.   +4 more
europepmc   +1 more source

Facile and Efficient Chemical Degradation of End-of-Life Tires into Value-Added Liquid Rubber

Qi Yang, Hua Zhang, Yu Sun, Xiaojian Liu, Lishuang Ma, Xuequan Zhang, Moris S. Eisen, Heng Liu   +7 more
openalex   +1 more source

Ethics-Relevant Values as Antecedents of Personality Change: Longitudinal Findings from the Life and Time Study

, 2019
Amber Gayle Thalmayer, Gerard Saucier, John C. Flournoy, Sanjay Srivastava   +3 more
openalex   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The construction and validation of a clinical predictive model for somatic symptom disorders in epilepsy patients. [PDF]

Front Neurol
Shen W, Zhang C, Pei X, Shen Z, Shen X.
europepmc   +1 more source

The value of health-related quality of life assessment in cancer clinical trials

, 2004
Fabio Efficace
openalex   +1 more source