Results 41 to 50 of about 8,748,539 (298)

Effects of Collagen Hydrolysate From Large Hybrid Sturgeon on Mitigating Ultraviolet B-Induced Photodamage

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Ultraviolet B (UVB) radiation leads to the excessive accumulation of reactive oxygen species (ROS), which subsequently promote inflammation, degradation of the extracellular matrix, and photoaging in skin.
Bei Chen   +10 more
doaj   +1 more source

QALYfying the value of life. [PDF]

open access: yesJournal of Medical Ethics, 1987
This paper argues that the Quality Adjusted Life Year or QALY is fatally flawed as a way of priority setting in health care and of dealing with the problem of scarce resources. In addition to showing why this is so the paper sets out a view of the moral constraints that govern the allocation of health resources and suggests reasons for a new attitude ...
openaire   +5 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

The value of statistical life and cost–benefit evaluations of landmine clearance in Cambodia [PDF]

open access: yes, 2010
Development agencies spend approximately US$ 400 million per year on landmine clearance. Yet many cost–benefit evaluations suggest that landmine clearance is socially wasteful because costs appear to far outweigh social benefits.
Cameron, Michael Patrick   +5 more
core   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Conceptualising the Value of Life in Bioethical Discourse: Sanctity vs Quality of Life

open access: yesStudia Warmińskie, 2023
The article deals with the problem of the value of life in the context of its understanding in bioethical discourse. Two different approaches are used to discuss the topic.
Oleksandr Horban, Ruslana Martych
doaj   +1 more source

THE NATURAL-LEGAL DIMENSION OF A PERSON’S STATUS [PDF]

open access: yesЭлектронное приложение к Российскому юридическому журналу, 2019
The natural law theory of a person as a substance of his own is presented in the article. The author analyzes historical and contemporary theories and states that any human rights and freedoms can be derived only from such a fundamental level, that a ...
Píry Martin
doaj  

Multi-Omics Analysis of Gene and Protein Candidates Possibly Related to Tetrodotoxin Accumulation in the Skin of Takifugu flavidus

open access: yesMarine Drugs, 2021
Pufferfish is increasingly regarded by many as a delicacy. However, the tetrodotoxin (TTX) that accumulates in its body can be lethal upon consumption by humans.
Huimin Feng   +8 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Proportion dominance in valuing lives: The role of deliberative thinking

open access: yesJudgment and Decision Making, 2016
Proportion responding (PR) is the preference for proportionally higher gains, such that the same absolute quantity is valued more as the reference group decreases. This research investigated this kind of proportion PR in decisions about saving lives (e.g.
André Mata
doaj   +1 more source

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