Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Optimisation of systems, safety and efficiency using simulation: a qualitative exploration of the value proposition for healthcare leaders. [PDF]
Clipperton S, McIntosh L, Janssens S.
europepmc +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The Value Proposition – Proposition or Imposition? Irish Banking Retail Context
The purpose of this research is to explore the level of importance consideration given to the development of a unique customer value proposition and the manner in which this proposition is proposed to or imposed on the customer within the Irish retail ...
Barrett, Jill
core
Navigating the value proposition of artificial intelligence in cardiovascular disease prevention. [PDF]
Shah A.
europepmc +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Adopting self-measured blood pressure monitoring in underserved primary care settings: a qualitative study using customer discovery and value proposition principles. [PDF]
Khatib R +5 more
europepmc +1 more source
The Value Proposition for Pathologists: A Population Health Approach. [PDF]
Ducatman BS +4 more
europepmc +1 more source
Could a Shigella vaccine impact long-term health outcomes?: Summary report of an expert meeting to inform a Shigella vaccine public health value proposition, March 24 and 29, 2021. [PDF]
Bagamian KH +18 more
europepmc +1 more source

