Results 161 to 170 of about 85,732 (247)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Mobilising the nursing student workforce in COVID-19: The value proposition. [PDF]

open access: yesCollegian, 2020
Bogossian F, McKenna L, Levett-Jones T.
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Revolutionizing Health Care Management: The 8Ps Value Proposition

open access: yes
In the intricate landscape of modern health care, the Genolier Swiss Medical Network introduces the 8Ps Value Proposition, a multifaceted framework aimed at transforming health care management.
Rebhan, Michael   +5 more
core  

Q&A. What Is Customer Value and How Do You Deliver It? [PDF]

open access: yesTechnology Innovation Management Review, 2012
Aparna Shanker
doaj  

Defining the value proposition in diagnostic technology: challenges and opportunities for its understanding and development - a review with a multiperspective reflective analysis. [PDF]

open access: yesFront Med (Lausanne)
Soukup T   +17 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The Value Proposition of Coordinated Population Cohorts Across Africa. [PDF]

open access: yesAnnu Rev Biomed Data Sci
Ramsay M   +4 more
europepmc   +1 more source

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