Results 91 to 100 of about 38,520,741 (357)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Nonlinear cross Gramians and gradient systems [PDF]

open access: yes, 2007
We study the notion of cross Gramians for non-linear gradient systems, using the characterization in terms of prolongation and gradient extension associated to the system.
Jacquelien M. A. Scherpen   +5 more
core   +1 more source

The relationship between talent management and value system of elementary school principals [PDF]

open access: yesپژوهش در نظام‌های آموزشی, 2018
This study aimed to examine talent management and its relationship with the value system of administrators. This research is descriptive and correlational with the aim of forecasting.
Mehdi Zirak   +3 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Getting value from Business Intelligence systems: A review and research agenda

open access: yesDecision Support Systems, 2017
Much of the research on Business Intelligence (BI) has examined the ability of BI systems to help organizations address challenges and opportunities.
V. Trieu
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Value based Agents for Social Simulation of Fishery Management

open access: yes, 2017
Although there have been many simulations of ecological systems that include social aspects of the persons involved, very little have considered the social aspects of the communities themselves as a separate system. In this paper we will integrate social,
Sub Intelligent Systems   +3 more
core  

"Jag söker ett värdelöst guld ett guld som gör värdelöst guldet, allt guld!"

open access: yesTidskrift för Litteraturvetenskap, 2014
”I am looking for a worthless gold / a gold that makes worthless / the gold, all gold!” Some entrances to the labyrinth of the literary value discourse This article examines the modern concept of literary value.
Anders Mortensen
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Finite-difference solutions of tenth-order boundary-value problems

open access: yes, 1994
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In this thesis finite difference methods are used to obtain numerical solutions for a class of high-order ordinary differential equations with applications ...
Siddiqui, Aijaz Ahmad
core  

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