Results 81 to 90 of about 38,520,741 (357)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Leadership Styles and Value Systems of School Principals
, 2014 The reforms conducted in the field of education are directed towards the changing manner of school management. The change is expressed in the transition from external supervision of schoolwork to the empowerment of school’s staff, with a change of the ...
Abu-Hussain Jamal
semanticscholar +1 more source
A conceptual system design and managerial complexity competency model [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Complex adaptive systems are usually difficult to design and control.
Amaechi, Austin Oguejiofor
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
La confiance, pierre angulaire du système éducatif en Finlande
Revue Internationale d’Éducation de Sèvres, 2016 This article looks at the way in which trust, in its philosophy and culture, manifests itself within the Finnish education system, drawing on examples concerning national-level processes and systems as well as local-level functions.
Irmeli Halinen, Hannele Niemi, Auli Toom
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Telematics and the transportation system's value
IFAC Proceedings Volumes, 2010 Abstract An approach from the economic science viewpoint is applied to the research on the influence of telematics development on the development of a transportation system. A qualitative instrument of such a research is the study of the creation, utilisation and perception of the value potential of a contemporary transportation system.
Ryszard Janecki +2 more
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Pliability and Viable Systems: Maintaining Value Under Changing Conditions
, 2015 As systems become more complex and have longer lifespans, they will likely encounter contextual variation or be themselves subject to change. Systems need to not only be feasible but viable as well.
Hastings, Daniel E +3 more
core +1 more source