Results 91 to 100 of about 31,154,554 (387)

Development and content validation of two new patient-reported outcome measures for endometriosis: the Endometriosis Symptom Diary (ESD) and Endometriosis Impact Scale (EIS)

Journal of Patient-Reported Outcomes, 2020
Background Endometriosis is a common, chronic, impactful condition in women of reproductive age. In the absence of established sensitive and specific biomarkers, disease severity is determined by patient-reported symptoms and impacts.
Adam Gater, Fiona Taylor, Christian Seitz, Christoph Gerlinger, Kamonthip Wichmann, Claudia Haberland   +5 more
doaj   +1 more source

Sensitivity, Specificity, and Predictive Values: Foundations, Pliabilities, and Pitfalls in Research and Practice

Frontiers in Public Health, 2017
Within the context of screening tests, it is important to avoid misconceptions about sensitivity, specificity, and predictive values. In this article, therefore, foundations are first established concerning these metrics along with the first of several ...
Robert Trevethan
semanticscholar   +1 more source

Diffusion technique stabilizes resistor values [PDF]

, 1966
Reduction of the contact resistance stabilizes the values, over a broad temperature range, of resistors used in linear integrated circuits.
Gallagher, R. C., Giuliano, M. N.
core   +1 more source

Recoverable Values for Independent Sets

, 2011
The notion of {\em recoverable value} was advocated in work of Feige, Immorlica, Mirrokni and Nazerzadeh [Approx 2009] as a measure of quality for approximation algorithms. There this concept was applied to facility location problems. In the current work
Feige, Uriel, Reichman, Daniel
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Qualitative interviews of patients with COPD and muscle weakness enrolled in a clinical trial evaluating a new anabolic treatment: patient perspectives of disease experience, trial participation and outcome assessments

Journal of Patient-Reported Outcomes
Background Chronic obstructive pulmonary disease (COPD) and muscle weakness can cause impaired physical function, significantly impacting patients’ health-related quality of life (HRQoL).
Maggie Tabberer, Nicola Williamson, Sophi Tatlock, Adam Gater, Rebecca Grimes, Chika Akinseye, David Neil, Aoife Mahon-Smith, Linda Nelsen   +8 more
doaj   +1 more source

Burden of Disease and Current Management of Dementia with Lewy Bodies: A Literature Review

Neurology and Therapy, 2019
Introduction A significant proportion of dementia is concretely estimated to be attributable to dementia with Lewy bodies (DLB)—one of the most common types of progressive dementia; however, there is a paucity of literature on this disease.
Amir Abbas Tahami Monfared, Genevieve Meier, Richard Perry, Darren Joe   +3 more
doaj   +1 more source

The value of print, the value of porn

Porn Studies, 2020
As the distribution of pornography has shifted online, the markets for DVDs and print magazines have drastically shrunk.
Daniel Cardoso, Susanna Paasonen
openaire   +3 more sources

Realizing moral values: on acting persons and moral values in Max Scheler's ethics [PDF]

, 2011
This article explores some aspects of how Max Scheler conceived of the relationship between persons and actions. The primary source to do so is Scheler’s Formalism in Ethics and Non-Formal Ethics of Values, but it will also be observed that the concept ...
Gescinska, Alicja Anna
core   +1 more source