Results 111 to 120 of about 4,008,475 (239)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Conversations about values in education in South Africa 2000 to 2005: A theoretical investigation [PDF]

open access: yes, 2011
Philosophiae Doctor - PhDThe 'conversations' under investigation have all been initiated by the National Department of Education (DoE) and are identified in this thesis as the following: the Values Report (2000); Opening Pathways (2002), the Manifesto ...
Small, Rosalie
core  

World Values Survey, Australia, 2012

open access: yes, 2017
The World Values Survey (WVS) series was designed to enable a crossnational, crosscultural comparison of values and norms on a wide variety of topics and to monitor changes in values and attitudes across the globe.
McAllister, Ian, Pietsch, Juliet
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Estimating the time required to reach HPV vaccination targets across Europe

open access: yesExpert Review of Vaccines
Background Cervical cancer (CC) is one of the most common causes of cancer-related deaths in women. The World Health Organization (WHO) has called for the CC elimination as a public health priority and has urged countries to achieve a 90% vaccine ...
Ilias Gountas   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Conference on Human Values in Medicine Southwest Regional Institute

open access: yes, 1973
The 1971 and 1972 sessions of the Institute on Human Values in Medicine were national conferences attended by humanists and medical educators who explored together ways in which human values could be studied in a meaningful, disciplined, relevant way as ...
McElhinney, Thomas K.   +1 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Human Values Teaching Programs for Health professionals

open access: yes, 1974
The nineteen teaching programs described in the following pages share the common goal of emphasizing human values as an important area of education in the health professions.
McElhinney, Thomas K.   +1 more
core  

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