Results 131 to 140 of about 10,025,038 (290)

Stability and change in values: A meta-analysis of longitudinal studies [PDF]

open access: yes, 2010
A meta-analysis of longitudinal studies was conducted to investigate stability and change in values across the life span. Both rank-order stability and mean-level change were investigated for all four different value categories.
Jin, Jing
core  

Asthma daytime and nighttime symptom diaries: content validity and qualitative exploration of meaningful change in patients with moderate-to-severe asthma

open access: yesJournal of Patient-Reported Outcomes
Background Asthma symptom severity can be assessed using the Asthma Daytime and Nighttime Symptom Diaries (ADSD and ANSD), which provide an accurate and standardized patient-reported option for symptom assessment during different periods of the day (i.e.
Tom Keeley   +6 more
doaj   +1 more source

The value of measuring value [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2015
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Teaching Ethics, the Humanities, and Human Values in Medical Schools: A Ten-Year Overview [PDF]

open access: yes, 1982
This report summarizes some of the more significant experiences and work of the Institute on Human Values in Medicine which has been assisted for a decade by successive grants from the National Endowment for the Humanities.
McElhinney, Thomas K.   +1 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The Role of Training in Organizations: a Comparative Case Study of Employees and Management Perspectives [PDF]

open access: yes, 2018
The transition to a more collaborative way of working brought a change in the role played by training in organizations, representing not exclusively a way to develop employees’ core competencies but also a strategic tool to govern team processes and ...
Polo, Federica   +3 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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