Results 151 to 160 of about 7,484,214 (317)

T $$ {}_{1\rho } $$ as a Biomarker for IDH1 Mutation Status in a Glioma Mouse Model. [PDF]

NMR Biomed
Ehler HJS, Sultana S, Davis C, Brewer K, Rioux J.   +4 more
europepmc   +1 more source

High Perceived-Value Requirements Engineering Practices for Outsourced Software Projects [PDF]

, 2015
Rodina Ahmad, Mohd Hairul Nizam Md Nasir, Javed Iqbal, Salmi Md Zahid   +3 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

To Possess or to Experience: Personal Values and Sociocultural Context Moderated Age Differences in Purchase Evaluations. [PDF]

Int J Psychol
Peng H, Li T.
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

How Well Do We Know VPDB-Part 2: Interlaboratory Assessment of Existing δ¹³C_VPDB Reference Materials. [PDF]

Rapid Commun Mass Spectrom
Moossen H, Steur PM, Camin F, Krajnc B, Enke A, Geilmann H, Paul D, Lange M, von Rein I, Meijer HAJ.   +9 more
europepmc   +1 more source

What US Healthcare Providers Value in Genomic Precision Medicine: A Discrete Choice Experiment [PDF]

, 2018
DS Dhanda, Dean A. Regier, DL Veenstra, Anirban Basu, Jonathan Saha, Nathaniel Hendrix, JJ Carlson   +6 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Survey of normalized CTDI_vol values across four major computed tomography vendors for use in the MIRDct software. [PDF]

J Appl Clin Med Phys
Dinwiddie LE, Baggett JM, Kofler JM, Kofler CB, Long DJ, Dawson RJ, Wehmeier SK, Wang Y, Ocampo-Ramos JC, Carter LM, Marquis H, Kayal G, Kesner AL, Bolch WE.   +13 more
europepmc   +1 more source

Triggering essential head tremor with sustained phonation: A clinical phenomenon with potential diagnostic value

, 2013
Brenton A. Wright, Monika Michalec, Elan D. Louis   +2 more
openalex   +1 more source