Results 231 to 240 of about 19,774,358 (302)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

4-Aminoquinolines block heme iron reactivity and interfere with artemisinin action. [PDF]

Elife
Rosenthal M, Goldberg DE.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Data gaps and outliers distort critical-slowing-down-based resilience indicators. [PDF]

Sci Adv
Liu T, Morr A, Bathiany S, Blaschke LL, Qian Z, Diao C, Smith T, Boers N.   +7 more
europepmc   +1 more source

Association of Liver Immune Status Index With the Nutritional Status and Prognosis in Patients With Cirrhosis. [PDF]

In Vivo
Yoshioka R, Nishimura T, Ikeda N, Aizawa N, Takashima T, Yuri Y, Kimura T, Tokura N, Nakano R, Shiomi H, Shinzaki S, Enomoto H.   +11 more
europepmc   +1 more source

A reference-based approach using whole-brain segmentation for image-derived PET input functions in CBF, OEF, and CMRO₂ quantification. [PDF]

J Cereb Blood Flow Metab
Kudomi N, Maeda Y, Kobata T, Morimoto M, Norikane T, Mitamura K, Manabe Y, Murao M, Yamamoto Y, Hatakeyama T, Nishiyama Y.   +10 more
europepmc   +1 more source