Results 141 to 150 of about 13,533,448 (310)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Values in teacher education Volume one
, 1996 Vol. 1 of 2SIGLEAvailable from British Library Document Supply Centre-DSC:q96/20576 / BLDSC - British Library Document Supply CentreGBUnited ...
National Association of Values in Education and Training (NAVET), Loughborough (United Kingdom) +1 more
core
Value’s of Mathematics Education and Citizenship Education [PDF]
, 2011 Currently, the Indonesian plane of life is miserable, inparticular on behavior. It is shown by the mushrooming acts of corruption, bribery, anarchy, public deceiving, traffic incompliance, etc. This mean any problem in nation character.
Hardi , Suyitno
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Integrating Anging Mammiri Cultural Values into Learning to Improve Students' Problem-Solving Skills
Problem-solving skills are essential in higher education, requiring contextual learning approaches grounded in cultural values. This study aimed to (1) identify students’ learning needs and formulate educational values within the Anging Mammiri culture, (
Rahayu, Sofia Ery +3 more
core +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Values in teacher education Volume 2
, 1996 Vol. 2 of 2SIGLEAvailable from British Library Document Supply Centre-DSC:q96/20577 / BLDSC - British Library Document Supply CentreGBUnited ...
National Association of Values in Education and Training (NAVET), Loughborough (United Kingdom) +1 more
core
Values education and moral development : what beginning teachers need to know [PDF]
, 2008 The notion of values education, that teachers explicitly teach students about morals and values, has been gaining momentum in Australian schools over the last five or so years.
Mergler, Amanda G.
core
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source