Results 151 to 160 of about 879,588 (251)

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Temporal Trends in Mitral Valve Repair Procedures and Outcomes Among Older U.S. Adults. [PDF]

JACC Adv
von Stein P, Cohen DJ, Leon MB, Popma A, von Stein J, Alu MC, Redfors B, Falah B, Granada JF, Popma JJ, Kundi H.   +10 more
europepmc   +1 more source

Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications

Advanced Science, EarlyView.
Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu, Xingyun Liu, Fangzhou Wang, Huili Ren, Chaojun Zhang, Ziyu Ren, Zunqi Liu, Jing Li   +7 more
wiley   +1 more source

Long-Term Outcomes of Mitral Valve Repair with Limited Resection in Active Endocarditis. [PDF]

J Cardiovasc Dev Dis
Haidari Z, Turaev I, Demircioglu E, Knipp S.   +3 more
europepmc   +1 more source

Oral Astilbin Nanogels Modulate Senescence‐Associated CD4+ T Cells and Promote Treg Induction in Aged Mice with Colitis

Advanced Science, EarlyView.
Fluorinated β‐glucan/pectin nanogels enable colon‐targeted oral delivery of astilbin through gastrointestinal protection, β‐glucanase‐responsive release, mucus penetration, and prolonged retention. The released astilbin attenuates senescence‐associated features of CD4+ T cells and promotes Treg responses, while the nanogel matrix modulates the gut ...
Lei Zhao, Xinyun Zhang, Qian Ren, Xue Song, Meifang Zhao, Rongshen Wang, Haocheng Du, Yan Chen, Peigen Xu, Jiangyun Liu, Jian Zhang, Jingjing Ma   +11 more
wiley   +1 more source

Managing mitral annular calcification-high-end robotic mitral valve repair for experienced surgeons. [PDF]

J Thorac Dis
Bonatti J, Kobayashi K.
europepmc   +1 more source

Massively Multiplexed Photonic Chip With Cross‐Channel Fusion For Harmonized Biosensing

Advanced Science, EarlyView.
We introduce a transformative sensing platform integrating photonic multiplexing with over 10 000 sensors and a deep‐learning framework that combines domain adaptation and cross‐channel fusion for harmonized operation across heterogeneous chips. The platform achieves 99.3% identification accuracy and relative prediction errors of 10−4$^{-4}$ for ...
Ivan Saetchnikov, Elina Tcherniavskaia, Andreas Ostendorf, Anton Saetchnikov   +3 more
wiley   +1 more source

Mitral Valve Repair vs. Replacement: Hemodynamics in Valve Surgery. [PDF]

Rev Cardiovasc Med
Zou M, Huang K, Wang X, Zhao S, Wu B, Hong X, Zhou X.   +6 more
europepmc   +1 more source

Prepolymerization Enables On‐Demand Viscosity Tuning for Xolography of Soft Hydrogels

Advanced Science, EarlyView.
A facile in situ prepolymerization strategy enables on‐demand viscosity tuning across three orders of magnitude without external thickeners, transforming low‐viscosity resins into printable formulations for Xolography. The approach suppresses sedimentation, lowers curing dose, enables high‐fidelity support‐free fabrication, and produces advanced ...
Xichuan Li, Marcus Reuter, Linguangze Zhuo, Xueheng Dai, Camille Tribout, Nathaniel Corrigan, Jin Zhang, Cyrille Boyer   +7 more
wiley   +1 more source

CeO2‐Based Electrocatalysts for the Oxygen Evolution Reaction: Design, Dynamic Mechanisms, and Electrolyte Adaptability

Advanced Science, EarlyView.
This Review shows how cerium oxide helps water‐splitting catalysts work better and last longer. It explains how CeO2 tunes electronic structure, oxygen‐vacancy behavior, and surface reconstruction, while adapting to alkaline, acidic, and seawater conditions.
Zhen Cui, Ailing Song, Zirui Cui, Manman Duanmu, Zhipeng Ma, Hao Liu, Guangjie Shao, Xinyi Tan, Guoxiu Wang, Hao Tian   +9 more
wiley   +1 more source