Results 51 to 60 of about 14,965,202 (290)
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Physico-chemical quality of the water resources in the van region [PDF]
In the present study, physico-chemical qualities of the water resources such as well, stream, fountain, tap and tank water obtained from the city of Van and its provinces (Erciş, Özalp, Saray, Muradiye, Çaldıran, Gürpınar, Gevaş and Edremit) were ...
Sema Ağaoğlu +3 more
doaj
Micromorphology and microstructural analysis of polyphase deformation of tills, West Runton [PDF]
Glacially deformed sediments have been studied intensely since the 1970’s (van der Meer and Menzies, 2011), and with this, the use of micromorphology as a component technique (Menzies and Maltman, 1992; van der Meer, 1993; Menzies, 2000; Phillips and ...
Ferguson, Amanda +2 more
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Water Quality Characteristics of Some Ponds in Van (Türkiye) Province
This study was conducted to investigate the physical and chemical properties of the waters of Lower Tulgalı, Oymaklı, Sırımlı, Morçiçek and Sağmalı ponds in Van province during the Autumn (November 2022), Spring (May 2023) and Summer (July 2023) seasons.
Muhammet Demir
doaj +1 more source
Bir arada yaşama kültürünün temelleri olan işbirliğini ve işbölümünü tehdit edenleri tenkil, te’dib ve tecrid vb. müeyyideler ile cezalandırma düşüncesi hapishane kurumlarının ihdasına sebep olmuştur.
Ercüment Topuz
doaj
TREX1, a predator for treating MSI‐H tumors?
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Kıbrıs Meselesinin Yerel Basına Yansımaları (1950-1960): Vansesi Gazetesi Örneği
Kıbrıs, tarihsel süreç içerisinde Akdeniz’de varlık gösteren bütün devletler için çok önemli olmuştur. Osmanlı Devleti, bu adanın Anadolu topraklarını savunmasındaki rolünü iyi bildiği için buradaki hâkimiyete çok önem vermiştir.
Mehmet Özalper
doaj
Agrobacterium-mediated transformation of Mycosphaerella fijiensis, the devastating Black Sigatoka pathogen of bananas [PDF]
Mycosphaerella fijiensis, M. musicola en M. eumusae veroorzaken de Sigatoka-ziekte in banaan. Op dit moment is de toepassing van fungiciden de enige optie om deze ziekte te bestrijden.
Adibon, H. +5 more
core +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source

