Results 51 to 60 of about 1,421,796 (268)
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Se evaluó la viabilidad financiera para la implementación de un sistema de producción de ganado de leche estabulado, en una finca que utiliza un sistema semiestabulado.
Luis Villalobos, Leonardo Rivera
doaj
Presenteizm ile Örgütsel Yabancılaşma İlişkisi: Van İli Otel İşletmeleri Örneği
Yerli ve yabancı literatürde presenteizm ile örgütsel yabancılaşma değişkenleri arasındaki ilişki ve etki düzeyini incelemeye yönelik çok az sayıda çalışma mevcuttur.
Songül Özer, Vedat Atay
doaj
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Ulaşım, turizm sektöründeki faaliyetlerin önemli bir parçasıdır. Bir ulaşım aracı olarak trenler, turistik deneyim oluşturmak amacıyla kullanılmaya başlanmıştır.
Uğur Saylan
doaj
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Birinci Dünya Savaşı öncesinde Van çevresindeki Ermenilerin Osmanlı Devleti'ndeki konumları ve karıştıkları olaylarla ilgili arşivlerde yeterince belge bulunmaktadır.
Masoumeh Daei
doaj
Van’ın, jeopolitik ve jeostratejik konumu itibariyle eski çağlardan itibaren bilinen bir tarihi vardır. Önceleri askeri bir garnizon hüviyetinde olan Van Kalesi ilerleyen zamanlarda, özellikle de Türk hâkimiyeti döneminde önce kale-şehir sonra da bütün ...
Orhan Kılıç
doaj
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source

