Results 31 to 40 of about 840,919 (175)

Iterative Chemical Engineering of Vancomycin Leads to Novel Vancomycin Analogs With a High in Vitro Therapeutic Index

Frontiers in Microbiology, 2018
Vancomycin is a glycopeptide antibiotic that inhibits transpeptidation during cell wall synthesis by binding to the D-Ala-D-Ala termini of lipid II. For long, it has been used as a last resort antibiotic.
Nigam M. Mishra, Izabela Stolarzewicz, Izabela Stolarzewicz, David Cannaerts, Joris Schuermans, Rob Lavigne, Yannick Looz, Bart Landuyt, Liliane Schoofs, Dominique Schols, Jan Paeshuyse, Peter Hickenbotham, Martha Clokie, Walter Luyten, Walter Luyten, Erik V. Van der Eycken, Erik V. Van der Eycken, Yves Briers, Yves Briers   +18 more
doaj   +1 more source

PREVALENCE OF LINEZOLID-RESISTANT VANCOMYCIN-RESISTANT ENTEROCOCCUS SPECIES (LRVRE) IN CLINICAL ISOLATES FROM TERTIARY CARE HOSPITAL OF NORTH INDIA – A REAL THREAT

International Journal of Infectious Diseases, 2023
Intro: Linezolid, an oxazolidinone antibiotic, was introduced early in 2000 as a new therapeutic option against gram positive cocci including vancomycin resistant enterococci (VRE).
S. Jain
doaj   +1 more source

Evaluation of Chromogenic Media in Detection of Vancomycin Resistant Enterococci [PDF]

Journal of Clinical and Diagnostic Research, 2014
Introduction: Vancomycin resistant Enterococci have become important nosocomial pathogens. So it is necessary to monitor continuously such infections in the hospitals.
Vijaya D., Vijaya S., Santhya S.T., Yashaswini M.K, Megha S.   +4 more
doaj   +1 more source

A study on glycopeptide-resistant genotypes among clinical isolates of Enterococcus with Van B phenotype

Advanced Biomedical Research, 2023
Background: Enterococci, although remarked as harmless commensals of the intestinal tract of humans and animals, have become a significant source of infection in hospitalized patients worldwide.The present study aimed to isolate and identify enterococci ...
Reena Rajan
doaj   +1 more source

High-level vancomycin-resistant enterococci causing hospital infections

, 1989
Nosocomial infection or colonization due to enterococci with high-levelresistance to vancomycin (minimal inhibitory concentrations [MICs] between 64and > 2000 mg/L) has occurred in 41 patients with renal disease.
Gilfillan, A, Collins, C H, George, R C, Uttley, A H C, Naidoo, J, Morrison, Donald, Heptonstall, J, Johnson, A P, Fitch, L E, Woodford, N   +9 more
core   +1 more source

Multidrug-resistant enterococci in the hospital environment: Detection of novel vancomycin-resistant E. faecium clone ST910 [PDF]

, 2016
Introduction: The role of the hospital environment as a reservoir of resistant bacteria in Tunisia has been poorly investigated; however, it could be responsible for the transmission of multidrug-resistant bacteria.
Ridha Bellaaj, Naouel Klibi, Abdellatif Boudabous, Carmen Lozano, Bellaaj, R., Carmen Torres, Ben Said, L., Klibi, N., Raoudha Dziri, Dziri, R. [0000-0003-1783-5672], Torres, C. [0000-0003-3709-1690], Lozano, C. [0000-0002-0048-9315], Boudabous, A., Ben Slama, K. [0000-0001-5745-3930], Karim Ben Slama, Leila Ben Said   +15 more
core   +2 more sources

Vancomycin-resistant enterococci and coagulase-negative staphylococci prevalence among patients attending at Felege Hiwot Comprehensive Specialized Hospital, Bahir Dar, Ethiopia.

PLoS ONE, 2021
BackgroundVancomycin resistant enterococci (VRE) and vancomycin resistance coagulase negative staphylococci (VRCoNS) are common pathogens causing difficult to treat health care associated infections (HAI).
Degu Ashagrie, Chalachew Genet, Bayeh Abera   +2 more
doaj   +1 more source

Antimicrobial susceptibility pattern of enterococci isolated from various clinical samples in a tertiary care hospital in India

IMC Journal of Medical Science, 2023
Background and objectives: Enterococci are significant human pathogens that are capable of causing various nosocomial infections. This study determined the antibiotic susceptibility pattern of enterococcal species isolated from various clinical specimens
Sameena Khan, Hardik Bansal, Nageswari Gandham, Shahzad Mirza, Chanda Vyawahare, Rajashri Patil, Sahjid Mukhida, Nikunja Kumar Das   +7 more
doaj   +1 more source

Gastrointestinal Colonization with Vancomycin-Resistant Enterococci in Hospitalized and Outpatients [PDF]

, 2014
BACKGROUND: The incidence of infection and intestinal colonization with vancomycin resistant enterococci (VRE) is increasing in many countries in the last decade.
Stojkovska, Snezana, Panovski, Nikola, Trajkovska-Dokic, Elena, Kaftandzieva, Ana, Kuzmanovska, Aneta   +4 more
core   +1 more source

Shapeshifting Antibiotics: Bullvalene Linked Vancomycin Dimers are Effective Against Multidrug-Resistant Gram-Positive Bacteria [PDF]

, 2022
The alarming rise in superbugs that are resistant to drugs of last resort, including vancomycin-resistant enterococci and staphylococci, has become a significant global health hazard. Here we report the click chemistry synthesis of an unprecedented class
Ewan, Murray, Jani R., Bolla, Thomas, Fallon, Tatiana P., Soares da Costa, Oussama, Yahiaoui, Alessandra, Ottonello, Paul, Williams, Jessica A., Wyllie, John E., Moses, Carol V. , Robinson   +9 more
core   +2 more sources