Results 181 to 190 of about 227,152 (290)

Lipid and polymer nanoparticles for drug delivery to bacterial biofilms [PDF]

open access: yes, 2014
Braeckmans, Kevin   +5 more
core   +2 more sources

A new branch of mammalian vitamin B6 metabolism: AKR1C‐mediated conversion of pyridoxal to pyridoxine and 4‐pyridoxolactone

open access: yesThe FEBS Journal, EarlyView.
Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito   +8 more
wiley   +1 more source

Meropenem‐Heparin Lock Therapy for Ochrobactrum intermedium Catheter‐Related Bloodstream Infection in a Pediatric Hemodialysis Patient: A Case Report and Literature Review

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background In pediatric hemodialysis patients with exhausted vascular access, managing rare pathogens like Ochrobactrum intermedium is challenging, often posing a dilemma between catheter removal and salvage attempts. There are few reports on the supported viability of meropenem‐heparin lock therapy for this purpose in pediatric patients. Case
Mônica Cristina Dutra Rodrigues   +4 more
wiley   +1 more source

Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen   +4 more
wiley   +1 more source

SanA Plays a Role in Peptidoglycan Integrity in Escherichia coli

open access: yesMolecular Microbiology, EarlyView.
SanA is a novel regulator of peptidoglycan synthesis, potentially through functional interplay with PBP1B‐dependent pathways. ABSTRACT Peptidoglycan synthesis and degradation are both essential for bacterial growth, and damaged peptidoglycan must be continuously repaired. In Escherichia coli, peptidoglycan required for cell elongation is synthesized by
Honoka Yamaguchi   +6 more
wiley   +1 more source

Salivary and Serum Cytokine Concentrations in Kidney Transplantation: A Prospective Study

open access: yesOral Diseases, EarlyView.
ABSTRACT Background Kidney transplant recipients (KTRs) experience immune modulation, which may lead to graft rejection and other adverse outcomes. Although serum cytokines are well‐established systemic immune markers, the role of salivary biomarkers has never been reported in the literature.
Luciano Miziara   +10 more
wiley   +1 more source

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