Results 51 to 60 of about 132,718 (290)

Glycopeptide Resistance in Gram-Positive Cocci: A Review

Interdisciplinary Perspectives on Infectious Diseases, 2012
Vancomycin-resistant enterococci (VRE) have emerged as important nosocomial pathogens in the past two decades all over the world and have seriously limited the choices available to clinicians for treating infections caused by these agents.
S. Sujatha, Ira Praharaj
doaj   +1 more source

High-level aminoglycoside resistance and reduced susceptibility to vancomycin in nosocomial enterococci

Journal of Global Infectious Diseases, 2010
Objectives: The objectives of the present study were to identify the species of enterococci isolated from nosocomial infections and to determine the antibiotic susceptibility pattern with reference to high-level aminoglycosides and vancomycin.
Luna Adhikari
doaj   +1 more source

Vancomycin-induced deletion of the methicillin resistance gene mecA in Staphylococcus aureus [PDF]

, 2017
Objective: To elucidate factors that contribute to the development of vancomycin resistance in methicillin-resistant Staphylococcus aureus (MRSA). Methods: Forty-nine MRSA isolates were subjected to passage selection with vancomycin to isolate mutants ...
Adhikari, Rajan P., Berger-Bächi, Brigitte, Cook, Gregory M., Kobayashi, Kere, Scales, Georgina C., Smith, John M. B.   +5 more
core  

Measures to eradicate multidrug-resistant organism outbreaks: How much does it cost? [PDF]

, 2015
This study aimed to assess the economic burden of infection control measures that succeeded in eradicating multidrug-resistant organisms (MDROs) in emerging epidemic contexts in hospital settings.
Birgand, GJC, Bourigault, C, Holmes, A, Iucet, JC, Lepelletier, D, Moore, L, Vella, V   +6 more
core   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Palmitoleic acid sensitizes vancomycin-resistant Staphylococcus aureus to vancomycin by outpacing the expression of resistance genes

Microbiology Spectrum
The rise in antibiotic resistance limits the availability of antibiotics to treat bacterial infections. Despite this, antibiotic development pipelines remain sparse which makes using adjuvants to reverse antibiotic resistance a promising therapeutic ...
Zajeba Tabashsum, Michelle Angeles-Solano, Ashelyn E. Sidders, Joshua B. Parsons, Sarah E. Rowe   +4 more
doaj   +1 more source

Two Screening Assays to Detect Vancomycin-Resistant Enterococcus spp.

Microbiology Research, 2022
Enterococci have become major nosocomial pathogens. An increasing number of these infections are as a result of vancomycin-resistant enterococci. Accurate detection of vancomycin-resistant enterococci (VRE) is important, so that appropriate therapy and ...
Beniamino T. Cenci-Goga, Musafiri Karama, Saeed El-Ashram, Cristina Saraiva, Juan García-Díez, Athanasios Chalias, Luca Grispoldi   +6 more
doaj   +1 more source

Impact of rapid mecA polymerase chain reaction rapid diagnostic testing for Staphylococcus aureus in a pediatric setting [PDF]

, 2018
Rapid molecular technology can detect the mecA resistance gene in Staphylococcus aureus (SA), predicting methicillin susceptibility in under one hour. In combination with antimicrobial stewardship program interventions in adults with SA bacteremia, rapid
Drwiega, Emily
core   +1 more source

High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]

, 2019
Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon, Camacho-Ortiz, Adrian, Flores-Trevino, Samantha, Garza-Gonzalez, Elvira, Maldonado-Garza, Hector Jesus, Morfin-Otero, Rayo, Rodriguez-Noriega, Eduardo, Rodrıguez-Noriega, Eduardo, Tijerina-Rodrıguez, Laura, Villarreal-Trevino, Licet   +9 more
core   +2 more sources

Enterococci and Vancomycin Resistance [PDF]

Clinical Infectious Diseases, 1998
The frequency of infections with multiply antibiotic-resistant gram-positive bacteria is increasing, and in some cases these organisms remain susceptible only to the glycopeptides vancomycin and teicoplanin. The appearance of transferable high-level glycopeptide resistance in enterococci--producing some strains that are now resistant to all available ...
openaire   +2 more sources