Results 101 to 110 of about 8,222 (211)

Evolution of phosphodiesterase type 5 inhibitors in treatment of erectile dysfunction in Taiwan

Urological Science, 2016
Erectile dysfunction (ED) is a prevalent form of male sexual dysfunction. Phosphodiesterase type 5 (PDE5) inhibitor is the first-line treatment for ED. Numerous well-designed and -conducted clinical trials and postmarketing studies have established the ...
Bang-Ping Jiann
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Erectile dysfunction drugs and oxidative stress in the liver of male rats

Toxicology Reports, 2015
Erectile dysfunction (ED) affected the lives of more than 300 million men worldwide. Erectile dysfunction drugs (EDD), known as phosphodiesterase inhibitors (PDEIs), have been used for treatment of ED.
Salah Sheweita, Basant Salama, Mostafa Hassan   +2 more
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Use of the KlADH3 promoter for the quantitative production of the murine PDE5A isoforms in the yeast Kluyveromyces lactis [PDF]

, 2017
Background: Phosphodiesterases (PDE) are a superfamily of enzymes that hydrolyse cyclic nucleotides (cAMP/ cGMP), signal molecules in transduction pathways regulating crucial aspects of cell life.
Biagioni, Stefano, Cardarelli, Silvia, Giorgi, Mauro, Malatesta, Francesco, Naro, Fabio, Saliola, Michele   +5 more
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Vardenafil for the treatment of erectile dysfunction: an overview of the clinical evidence

Clinical Interventions in Aging, 2009
Antonio Martín Morales1, Vincenzo Mirone2, John Dean3, Pierre Costa41Department of Urology, Hospital Carlos Haya, Malaga, Spain; 2Department of Urology, University Federico II, Naples, Italy; 3St.
Antonio Martín Morales, Vincenzo Mirone, John Dean, et al   +3 more
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Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. [PDF]

, 2014
BackgroundIndividuals with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease, partly due to systemic inflammation and endothelial dysfunction.
Del Puerto, Gus, Ganz, Peter, Graf, Jonathan, Grunfeld, Carl, Hsue, Priscilla Y, Imboden, John, Nitta, Elaine, Scherzer, Rebecca, Schnell Heringer, Amanda, Shigenaga, Judy, Wu, Yuaner   +10 more
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Vasa Nervorum in rat major pelvic ganglion are innervated by nitrergic nerve fibers [PDF]

, 2013
INTRODUCTION The vasa nervorum comprises a network of small diameter blood vessels that provide blood supply to nerves and ganglia. The cell bodies of autonomic nerves innervating the urogenital organs are housed in the major pelvic ganglia (MPG) in rats.
Ames, Andersson, Appenzeller, Asif Muneer, Benesova, Benesova, Cameron, Cameron, Cameron, Cellek, Cellek, Cellek, Cellek, Chandrasekharan, Chantrain, Chung, Dail, Dashwood, Dixon, Giuliano, Gonzalez‐Hernandez, Hackett, Hlaing, Iadecola, Kalsi, Karl A. Beetson, Kavdia, Kedia, Kobayashi, Low, Mary A. Cotter, Mbaku, McManis, Melikian, Norman E. Cameron, Padma‐Nathan, Porst, Saenz de Tejada, Schirar, Selim Cellek, Sonntag, Stephanie F. Smith, Stuehr, Tabatai, Toda, Toda, Toda, Toque, Vitullo, Wang   +49 more
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Influence of regular use of vardenafil on endothelial and erectile functions in patients with arteriogenic erectile dysfunction

Терапевтический архив, 2009
Aim. To study the influence of long-term of vardenafil use on endothelial and erectile functions in patients with arteriogenic erectile dysfunction (ED) Subjects and methods. The study included 74 arteriogenic ED patients (mean age 57.4 ± 4.7 years).
Safar Israilovich Gamidov, Dmitriy Viktorovich Shcherbakov, Regina Amirbekovna Tkhagapsoeva, Roman Vladimirovich Koroteev, S I Gamidov, D V Shcherbakov, R A Tkhagapsoyeva, R V Koroteyev   +7 more
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Patient Insight and Treatment Expectations in Erectile Dysfunction [PDF]

European Medical Journal, 2016
In the literature, a strong preference towards pharmacological management with oral phosphodiesterase type 5 (PDE5) inhibitors has been demonstrated in men with erectile dysfunction (ED) versus other methods. However, following pharmacological management,
Hartmut Porst
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PDE5 Inhibitors As Potential Tools In The Treatment Of Cystic Fibrosis

Frontiers in Pharmacology, 2012
Despite great advances in the understanding of the genetics and pathophysiology of cystic fibrosis (CF), there is still no cure for the disease. Using phosphodiesterase type 5 (PDE5) inhibitors, we and others have provided evidence of rescued F508del ...
Sabrina eNoel, Barbara eDhooghe, Teresinha eLeal   +2 more
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Comparison of efficacy for erectile function and lower urinary tract symptoms of tadalafil 20 mg on-demand and 5 mg once daily in patients with erectile dysfunction [PDF]

, 2012
Aim: To compare the improvement in erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) as well as safety of tadalafil dosed at 20 mg on-demand and 5 mg once daily among ED patients.
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