Results 41 to 50 of about 19,681 (252)

Estimation of risk of neuropsychiatric adverse events from varenicline, bupropion and nicotine patch versus placebo: secondary analysis of results from the EAGLES trial using Bayes factors

Addiction, 2021
Background and Aims Analysed using classical frequentist hypothesis testing with alpha set to 0.05, the Evaluating Adverse Events in a Global Smoking Cessation Study (EAGLES) did not find enough evidence to reject the hypothesis of no difference in ...
E. Beard, S. Jackson, R. Anthenelli, N. Benowitz, Lisa B. St. Aubin, T. McRae, D. Lawrence, C. Russ, A. Krishen, A. E. Evins, R. West   +10 more
semanticscholar   +1 more source

Evaluation of reproductive and renal toxicity of varenicline in male rats [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): Varenicline is a selective partial agonist for the nicotinic acetylcholine receptor a4b2 subtype, which is widely used to treat smoking addiction. However, there is still no data about its potential toxic effects on tissues.
Fatih OĞUZ, Ali Beytur, Elif Taşlıdere, Hakan Parlakpınar, Hilal Oğuz, Alaaddin Polat, İbrahim Topcu, Nigar Vardi, Engin Burak Selcuk   +8 more
doaj   +1 more source

Efficacy and safety of pharmacotherapies for smoking cessation in anxiety disorders: Subgroup analysis of the randomized, active- and placebo-controlled EAGLES trial. [PDF]

, 2020
BackgroundSmoking rates are high in adults with anxiety disorders (ADs), yet little is known about the safety and efficacy of smoking-cessation pharmacotherapies in this group.MethodsPost hoc analyses in 712 smokers with AD (posttraumatic stress disorder
Anthenelli, Robert M, Ayers, Catherine R, Evins, A Eden, Heffner, Jaimee L, Lawrence, David, McRae, Thomas, Russ, Cristina   +6 more
core  

Nicotine-replacement therapy: A proven treatment for smoking cessation [PDF]

, 2010
Smoking is a major cause of cardiovascular diseases, respiratory diseases and cancer. Despite the high prevalence of smokers worldwide, smokers are often neglected and not offered effective assistance with quitting their habits. In order to overcome this
Robson, Noorzurani
core   +1 more source

Varenicline is More Effective than Nicotine Replacement Therapy During Pregnancy: Findings from the Smoking MUMS (Maternal Use of Medications and Safety) Study

International Journal of Population Data Science, 2018
Introduction Studies in the general population suggest that varenicline is more effective than nicotine replacement therapy (NRT) for smoking cessation.
Stephanie KY Choi, Duong T Tran, David B Preen, Deborah Randall, Anna Kemp-Casey, Kristjana Einarsdottir, Louisa R Jorm, Alys Havard   +7 more
doaj   +1 more source

Using the Social-Local-Mobile App for Smoking Cessation in the SmokeFreeBrain Project: Protocol for a Randomized Controlled Trial [PDF]

, 2018
Background: Smoking is considered the main cause of preventable illness and early deaths worldwide. The treatment usually prescribed to people who wish to quit smoking is a multidisciplinary intervention, combining both psychological advice and ...
Bamidis, Panagiotis D., Carrasco Hernández, Laura, Civit Balcells, Antón, Fernández Luque, Luis, Hors Fraile, Santiago, Jódar Sánchez, Francisco, Mesa González, Marco Antonio, Moreno Conde, Jesús, Núñez Benjumea, Francisco José, Ortega Ruiz, Francisco, Parra Calderón, Carlos Luis   +10 more
core   +3 more sources

Alcohol use disorder severity moderates clinical response to varenicline.

Alcoholism: Clinical and Experimental Research, 2021
BACKGROUND In a multisite clinical trial, varenicline was effective in reducing drinking in both smoking- and nonsmoking patients with alcohol dependence.
S. Donato, ReJoyce Green, L. Ray
semanticscholar   +1 more source

Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression

Journal of Pharmacological Sciences, 2020
Varenicline is a widely used and effective drug for smoking cessation. We previously reported that varenicline aggravates atherosclerosis in apolipoprotein E knockout (ApoE KO) mice.
Mitsuhisa Koga, Yuki Kanaoka, Mana Okamoto, Yuki Nakao, Koshun Inada, Saki Takayama, Yasufumi Kataoka, Atsushi Yamauchi   +7 more
doaj  

Electronic Cigarettes vs Varenicline for Smoking Cessation in Adults: A Randomized Clinical Trial.

JAMA Intern Med
Importance Little is known about the relative effectiveness of nicotine-containing electronic cigarettes (ECs) compared with varenicline as smoking cessation aids. Objective To determine the relative effectiveness of ECs in smoking cessation. Design,
Tuisku A, Rahkola M, Nieminen P, Toljamo T.   +3 more
europepmc   +2 more sources

VARENICLINE IN PATIENTS WITH CARDIOVASCULAR DISEASES – FRIEND OR ENEMY?

Рациональная фармакотерапия в кардиологии, 2015
The problem of varenicline use in patients with cardiovascular diseases is discussed. Results of large clinical trials and meta-analyses with varenicline have proven its high efficacy for treatment of nicotine addiction in adults and a small number of ...
Yu. V. Lukina, S. Yu. Martsevich
doaj   +3 more sources