Results 71 to 80 of about 19,420 (250)
A genome-wide association study of nausea incidence in varenicline-treated cigarette smokers.
Nicotine & Tobacco Research, 2021 INTRODUCTION Varenicline is the most efficacious smoking cessation treatment, however long-term cessation rates tend to be
Meghan J. Chenoweth +3 more
semanticscholar +1 more source
The cost-effectiveness of smoking cessation support delivered by mobile phone text messaging: Txt2stop. [PDF]
, 2012 BACKGROUND: The txt2stop trial has shown that mobile-phone-based smoking cessation support doubles biochemically validated quitting at 6 months. This study examines the cost-effectiveness of smoking cessation support delivered by mobile phone text ...
Cairns, John +5 more
core +2 more sources
Drug Testing and Analysis, Volume 17, Issue 9, Page 1772-1784, September 2025.The study provides information about the impact of physiological gastric conditions on the unbeneficial occurrence of nitrosamine drug substance–related impurities (NDSRIs). Both main factors for nitrosation in the form of acidic conditions and the presence of nitrite were adequately chosen for triggering the conversion of drug compounds into NDSRIs ...
Matthias Vogel +5 more
wiley +1 more source
Varenicline Induced Psychosis [PDF]
Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 (2012). Varenicline Induced Psychosis. Klinik Psikofarmakoloji Bulteni-Bulletin of Clinical Psychopharmacology: Vol. 22, No. 1, pp. 110-111.
Bilge Burçak Annagür +2 more
openaire +2 more sources
Addiction Biology, Volume 30, Issue 9, September 2025.ABSTRACT Chronic nicotine administration leads to neuroadaptations, an important process in nicotine and tobacco dependence for which treatments are limited. The cysteine pro‐drug, N‐acetyl‐cysteine (NAC), is a promising glutamatergic agent that has shown some clinical efficacy in reducing nicotine use in humans.
Kelsey Stoddart +5 more
wiley +1 more source
Varenicline in the treatment of tobacco dependence
Neuropsychiatric Disease and Treatment, 2008 Varenicline, a partial agonist of alpha(4)beta(2) nicotinic acetylcholine receptors, is the most recently approved drug for smoking cessation. This paper reviews the outcomes of Phase 2 and Phase 3 clinical trials that assess the efficacy of varenicline in comparison to placebo and other smoking cessation pharmacotherapies, ie, sustained-release ...
John R. Hughes, Karl Fagerström
openaire +5 more sources
Electronic Cigarettes vs Varenicline for Smoking Cessation in Adults: A Randomized Clinical Trial.
JAMA Intern MedImportance Little is known about the relative effectiveness of nicotine-containing electronic cigarettes (ECs) compared with varenicline as smoking cessation aids. Objective To determine the relative effectiveness of ECs in smoking cessation. Design,
Tuisku A +3 more
europepmc +2 more sources
Combining Varenicline (Chantix) with Naltrexone Decreases Alcohol Drinking More Effectively Than Does Either Drug Alone in a Rodent Model of Alcoholism [PDF]
, 2016 Background This study examined whether varenicline (VAR), or naltrexone (NTX), alone or in combination, reduces alcohol drinking in alcohol-preferring (P) rats with a genetic predisposition toward high voluntary alcohol intake.
Dilley, Julian E. +6 more
core +3 more sources
Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease
Movement Disorders, Volume 40, Issue 8, Page 1584-1594, August 2025.Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou +6 more
wiley +1 more source
Journal of Clinical Psychopharmacology, 2019 Background Neuropsychiatric safety and relative efficacy of varenicline, bupropion, and transdermal nicotine patch (NRT) in those with psychiatric disorders are of interest.
A. E. Evins +9 more
semanticscholar +1 more source