Results 71 to 80 of about 3,116,070 (323)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Addition of 24‐Hour Heart Rate Variability Parameters to the Cardiovascular Health Study Stroke Risk Score and Prediction of Incident Stroke: The Cardiovascular Health Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundHeart rate variability (HRV) characterizes cardiac autonomic functioning. The association of HRV with stroke is uncertain. We examined whether 24‐hour HRV added predictive value to the Cardiovascular Health Study clinical stroke risk score (CHS‐
Rohan K. Bodapati, Jorge R. Kizer, Willem J. Kop, Hooman Kamel, Phyllis K. Stein   +4 more
doaj   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Analysis of Heart Rate Variability and Implication of Different Factors on Heart Rate Variability

Current Cardiology Reviews, 2020
Background The heart is the central organ of the circulatory system, which maintains the flow of blood along with the transport of nutrients to different cells and tissues. A well-functioning cardiac state is a complicated mode of changeability.
Reena Tiwari, Ravindra Kumar, Sujata Malik, T. Raj, Punit Kumar   +4 more
semanticscholar   +1 more source

Analytic extensions of functions of Cayley-Dickson variables [PDF]

arXiv, 2018
Analytic approximations of functions of Cayley-Dickson variables are investigated. The case of functions of complexified Cayley-Dickson variables is also encompassed. Moreover, extensions of functions of Cayley-Dickson variables are studied.
arxiv  

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Dynamics of Stride Interval Characteristics during Continuous Stairmill Climbing

Frontiers in Physiology, 2017
It has been shown that statistical persistence in stride intervals characteristics exist during walking, running and cycling and were speed-dependent among healthy young adults.
Peter C. Raffalt, Peter C. Raffalt, Srikant Vallabhajosula, Jessica J. Renz, Mukul Mukherjee, Nicholas Stergiou, Nicholas Stergiou   +6 more
doaj   +1 more source

Precipitation variability increases in a warmer climate

Scientific Reports, 2017
Understanding changes in precipitation variability is essential for a complete explanation of the hydrologic cycle’s response to warming and its impacts.
A. Pendergrass, R. Knutti, F. Lehner, C. Deser, B. Sanderson   +4 more
semanticscholar   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Selective engagement of long-latency reflexes in postural control through wobble board training

Scientific Reports
Long-latency reflexes (LLRs) are critical precursors to intricate postural coordination of muscular adaptations that sustain equilibrium following abrupt disturbances.
Theodore Deligiannis, Mahsa Barfi, Brian Schlattmann, Ken Kiyono, Damian G. Kelty-Stephen, Madhur Mangalam   +5 more
doaj   +1 more source