Results 61 to 70 of about 2,254,450 (359)
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
VARIABLE AND FIXED COSTS IN COMPANY MANAGEMENT [PDF]
The cost absorbs all the expenses of production for a company at acertain level of the activity. For eliminating the influence of the fixed costs’sabsorbtion and for a better supervision of other causes of digressions, the managerscan apply the method of
Sorin Briciu
core
ANALISIS PENENTUAN HARGA JUAL GUNA MENINGKATKAN PROFITABILITAS PADA PERUSAHAAN ROKOK PT. JATI MESEM MALANG [PDF]
This research is a case study in cigarette company PT. Teak mesem Malang with the title "Selling Pricing Analysis To Improve Profitability On Cigarette Company PT. Teak mesem Malang.
Stiyoningsih, Nuning
core
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Radar Detectors, Fixed and Variable Costs of Crime [PDF]
Raising the sanction will always reduce the utility of the criminal. However, raising the sanction will not always lead to less crime, and may lead to more crime.
Timothy Stanley
core
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Duality Theory for Variable Costs in Joint Production [PDF]
Duality methods for incomplete systems of consumer demand equations are adapted to the dual structure of variable cost functions in joint production. This allows the identification of necessary and sufficient restrictions on technology and cost so that ...
Jeffrey LaFrance, Rulon Pope
core
RESERVE FLEET INDEXED TO EXOGENOUS COST VARIABLES
Identifying the optimal time to replace a passenger bus in a buses fleet has implications on the size of the reserve fleet. Such calculations rest on endogenous and exogenous economic variables: the former include operating and maintenance costs and bus depreciation; the latter include market imponderables such as the inflation and real discount rates,
Nogueira Raposo, Hugo David +3 more
openaire +6 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Comparison of the actual costs during removal of concrete layer by high-speed water jets
This paper describes the process of possible evaluation of costs of using high speed water jet technology for concrete removal methods. High speed water jet technology is a progressive technology of removing damaged concrete used in civil engineering ...
Rudolf Hela +6 more
doaj +1 more source

