Results 71 to 80 of about 139,960 (305)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Perturbed subcritical Dirichlet problems with variable exponents

open access: yesElectronic Journal of Differential Equations, 2016
We study a class of nonhomogeneous elliptic problems with Dirichlet boundary condition and involving the p(x)-Laplace operator and power-type nonlinear terms with variable exponent.
Ramzi Alsaedi
doaj  

Analytic multivariate generating function for random multiplicative cascade processes

open access: yes, 1998
We have found an analytic expression for the multivariate generating function governing all n-point statistics of random multiplicative cascade processes.
Eggers, Hans C.   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Weak type estimates of Hardy–Littlewood maximal operator on local Morrey spaces associated with ball quasi-Banach function spaces

open access: yesResults in Applied Mathematics
This paper proves the weak type estimates of the Hardy–Littlewood maximal operator on local Morrey spaces associated with ball quasi-Banach function spaces.
HanLin Li, Jiang Zhou
doaj   +1 more source

Existence of solutions for critical systems with variable exponents

open access: yesMathematical Modelling and Analysis, 2018
In this work, we deal with elliptic systems under critical growth conditions on the nonlinearities. Using a variant of concentration-compactness principle, we prove an existence result.
Hadjira Lalilia, Saadia Tas, Ali Djellit
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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