Results 121 to 130 of about 6,512,302 (308)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Variable Mass Dynamics Of Celestial Bodies Revisited With Modification [PDF]
Whittaker1 introduced variable mass dynamics in Celestial Mechanics obtaining as Jacobi –Lagrange counterpart2 a differential equation involving the moment of inertia, where time is taken as the independent variable.
Maitra, Soumendra Nath
core +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
We propose a generic algorithm for the construction of efficient reversible variable-length codes (RVLCs) and variable-length error-correcting (VLEC) codes, which optimizes the codeword length distribution.
Wang, J., Yang, L-L., Hanzo, L.
core +1 more source
Variability of millimeter wavelength continuum emission from Class II protoplanetary disks is extremely rare, and when detected, it is usually interpreted as originating from nonthermal emission mechanisms that relate to the host star itself rather than ...
James M. Miley +17 more
doaj +1 more source
Probing the Composition, Assembly and Activity of Protein Molecular Machines using Native Mass Spectrometry [PDF]
Native mass spectrometry and mass spectrometry in general, are powerful analytical tools for studying proteins and protein complexes. Native mass spectrometry may provide accurate mass measurements of large macromolecular assemblies enabling the ...
van de Waterbeemd, M.J. +2 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Imaging mass spectrometry of polymeric materials [PDF]
Imaging mass spectrometry (MS) is a technique that makes images of molecular distributions at surfaces based on mass spectral information. At a range (typically a raster) of positions, mass spectra are measured from the surface giving a characteristic ...
Klerk, L.A. +3 more
core +1 more source

