Results 101 to 110 of about 3,490,672 (298)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Investigation of variable thermo-physical properties of viscoelastic rheology: A Galerkin finite element approach

open access: yesAIP Advances, 2018
Galerkin finite element (GFEM) algorithm is implemented to investigate the variable viscosity, variable thermal conductivity and variable mass diffusion coefficient on viscoelasticity and non-Newtonian rheology of Maxwell fluid.
Imran Haider Qureshi   +4 more
doaj   +1 more source

The variable-mass seepage law of broken porous rock: an experimental study

open access: yesGeomatics, Natural Hazards & Risk, 2020
Induced by tunnel excavation, the particles constantly shift in broken porous rock of faults until failure occurs, which provides channels for water inrush. Therefore, it is essential to investigate the particle migration of broken porous rock.
Yingchao Wang   +4 more
doaj   +1 more source

Mass measurement in boosted decay systems at hadron colliders

open access: yes, 2011
We report a new possibility of using the $\mct2$ (Constransverse mass) variable for mass measurement in single step decay chains involving missing particles with moderate transverse momentum. We show that its experimental feasibility is enhanced compared
Cho, Won Sang   +2 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Revisiting the D-meson hadroproduction in general-mass variable flavour number scheme

open access: yesJournal of High Energy Physics, 2018
We introduce a novel realization of the open heavy-flavour hadroproduction in general-mass variable flavour number scheme at next-to-leading order in perturbative QCD.
Ilkka Helenius, Hannu Paukkunen
doaj   +1 more source

Home - About - Disclaimer - Privacy