Results 111 to 120 of about 221,965 (288)

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini   +28 more
wiley   +1 more source

Heterogeneous Vehicle Routing Method Based on Variable Step Multi‑neighborhood Search

open access: yesShuju Caiji Yu Chuli
The vehicle routing problem is a classic combinatorial optimization problem that has been proven to be NP‑hard. It is widely applied to the fields of transportation logistics and intelligent manufacturing.
ZHENG Jiyuan   +3 more
doaj   +1 more source

A Partial Taxonomy of Substitutability and Interchangeability [PDF]

open access: yes, 2010
Substitutability, interchangeability and related concepts in Constraint Programming were introduced approximately twenty years ago and have given rise to considerable subsequent research.
Berthe Y. Choueiry   +8 more
core   +3 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

An Improved Particle Swarm Optimization Algorithm Based on Variable Neighborhood Search

open access: yesMathematics
Various metaheuristic algorithms inspired by nature have been designed to deal with a variety of practical optimization problems. As an excellent metaheuristic algorithm, the improved particle swarm optimization algorithm based on grouping (IPSO) has ...
Hao Li   +3 more
doaj   +1 more source

Combinatorial optimization and metaheuristics [PDF]

open access: yes, 2006
Today, combinatorial optimization is one of the youngest and most active areas of discrete mathematics. It is a branch of optimization in applied mathematics and computer science, related to operational research, algorithm theory and computational ...
Consoli, S, Darby-Dowman, K
core  

Reactive variable neighborhood search

open access: yes, 2018
Recent works have shown that the variable neighborhood search (VNS) algorithm can be improved by using a reactive component. A component is reactive if its behavior changes dynamically depending on the information obtained from the current run, or depending on the instance to solve.
Thevenin, Simon, Zufferey, Nicolas
openaire   +1 more source

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