Results 91 to 100 of about 5,119,730 (291)
combinatorial optimization, principal component analysis, variable selection, variable neighborhood search, tabu search,
Douglas Steinley +2 more
core +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Split-merge:using exponential neighborhood search for scheduling a batching machine [PDF]
, 2015 We address the problem of scheduling a single batching machine to minimize the maximum lateness with a constraint restricting the batch size. A solution for this NP-hard problem is defined by a selection of jobs for each batch and an ordering of those ...
Song, Xiang +3 more
core +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
, 2019 As failure and reliability predictions play a significant role in production systems they have caught the attention of researchers. In this study, Support Vector Regression (SVR), which is known as a powerful neural network method, is developed as a way ...
Babagolzadeh, Mahla +3 more
core +1 more source
Large Neighborhood Search [PDF]
, 2010 Heuristics based on large neighborhood search have recently shown outstanding results in solving various transportation and scheduling problems. Large neighborhood search methods explore a complex neighborhood by use of heuristics.
David Pisinger +3 more
core +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
An efficient meta-heuristic algorithm for solving capacitated vehicle routing problem
IJAIN (International Journal of Advances in Intelligent Informatics), 2018 This work aims to develop an enhanced Perturbation based Variable Neighborhood Search with Adaptive Selection Mechanism (PVNS ASM) to solve the capacitated vehicle routing problem (CVRP).
Alfian Faiz +2 more
doaj +1 more source
Exploring variable neighborhood search for automatic algorithm configuration
, 2017 Methods for automatic algorithm configuration integrate some search mechanism for generating candidate algorithm configurations and mechanisms for handling the stochasticity of the algorithm configuration problem.
Thomas Stützle +3 more
core +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source