Results 71 to 80 of about 221,965 (288)

Penerapan Algoritma Variable Neighborhood Search untuk Optimasi Pemilihan Produk Skincare

Jurnal Teknologi dan Sistem Informasi
Pertumbuhan industri skincare di Indonesia mendorong kebutuhan akan sistem pemilihan produk yang mampu membantu konsumen memilih kombinasi produk yang sesuai dengan jenis kulit dan batas anggaran.
Greta Septy Purwiantono, Amalia Utamima
doaj   +1 more source

Combinatorial GVNS (General Variable Neighborhood Search) Optimization for Dynamic Garbage Collection

Algorithms, 2018
General variable neighborhood search (GVNS) is a well known and widely used metaheuristic for efficiently solving many NP-hard combinatorial optimization problems. We propose a novel extension of the conventional GVNS. Our approach incorporates ideas and
Christos Papalitsas, Panayiotis Karakostas, Theodore Andronikos, Spyros Sioutas, Konstantinos Giannakis   +4 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

The robust single machine scheduling problem with uncertain release and processing times [PDF]

, 2014
In this work, we study the single machine scheduling problem with uncertain release times and processing times of jobs. We adopt a robust scheduling approach, in which the measure of robustness to be minimized for a given sequence of jobs is the worst ...
Bierlaire, Michel, Erera, Alan L., Umang, Nitish   +2 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

An efficient General Variable Neighborhood Search for large Travelling Salesman Problem with Time Windows [PDF]

Yugoslav Journal of Operations Research, 2013
General Variable Neighborhood Search (GVNS) is shown to be a powerful and robust methodology for solving travelling salesman and vehicle routing problems.
Mladenović Nenad, Todosijević Raca, Urošević Dragan   +2 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

A Hybrid Method based on SA and VNS Algorithms for Solving DAP in DDS [PDF]

Computer Science Journal of Moldova, 2021
Data allocation problem (DAP) is of great importance in distributed database systems (DDS). Minimizing the total cost of transactions and queries is the main objective of DAP which is mostly affected by the volume of transmitting data through the system.
Nasser Lotfi, Jamshid Tamouk
doaj