Results 151 to 160 of about 5,702,760 (334)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

The Puzzle of V407 Cygni

open access: yesActa Polytechnica, 2011
We discuss the nature and recent observations (optical and gamma-rays) of symbiotics binary/Mira variable V407 Cygni. In addition we discuss another object of similar category, namely the variable star FY Aql with possible association with an eruptive ...
R. Hudec
doaj  

An Episode of Occultation Events in Gaia21bcv

open access: yesThe Astronomical Journal
A previously unremarkable star near the Canis Major OB1/R1 association underwent an episode of multiple deep brightness minima. Light curves based on archival Gaia, Zwicky Transient Facility (ZTF), and NEOWISE data and additional observations from the ...
Klaus W. Hodapp   +6 more
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Photometric Flickering of the CH CYG IN 2018

open access: yesEast European Journal of Physics
Photometric observations of the CH Cyg symbiotic star were conducted using the Zeiss 600 telescope at the ShAO (Shamakhy Astrophysical Observatory) between 06.07.2018 and 16.09.2018 over the course of 17 nights with the V-filter. The light curve for this
Kh.M. Mikailov, R.T. Mammadov
doaj   +1 more source

Discovery of a massive variable star with Z = Z⊙/36 in the galaxy DDO 68 [PDF]

open access: green, 2008
S. A. Pustilnik   +3 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Caught in the Act: Observations of the Double-mode RR Lyrae V338 Boo during the Disappearance of a Pulsation Mode

open access: yesThe Astrophysical Journal
New results on the behavior of the double-mode RR Lyrae V338 Boo are presented. The Transiting Exoplanet Survey Satellite (TESS) observed this star again in 2022, and an observing campaign of the American Association of Variable Star Observers (AAVSO ...
Kenneth Carrell   +15 more
doaj   +1 more source

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