Results 121 to 130 of about 4,932,223 (296)
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Pulsating stars are universally recognized as precise distance indicators and tracers of stellar populations. Their variability, combined with well-defined relationships between pulsation properties and intrinsic evolutionary parameters such as ...
Giulia De Somma +3 more
doaj +1 more source
Long-period variable AGB stars in a field towards the Galactic Bulge [PDF]
J. A. D. L. Blommaert +4 more
openalex +1 more source
Automatic detection of plateau phases in light curves of variable stars [PDF]
Anastasia Lavrukhina +2 more
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Red Variable Stars—“Variab. Cygni (Birmingham), 1881,” &c [PDF]
John Birmingham
openalex +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
New results on the behavior of the double-mode RR Lyrae V338 Boo are presented. The Transiting Exoplanet Survey Satellite (TESS) observed this star again in 2022, and an observing campaign of the American Association of Variable Star Observers (AAVSO ...
Kenneth Carrell +15 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source

