Make‐Use‐Remake: Toward Indefinite Low‐Temperature Material Loops
We introduce a regenerable materials platform built from microparticles bound by a temperature‐responsive polymer shell, enabling strong, processable structures from diverse feedstocks. The material is shaped at low temperatures (80°C) using common manufacturing methods and reprocessed repeatedly in the presence of water, demonstrating stable ...
Nikola Křivánková +2 more
wiley +1 more source
Design of a New Nonlinear Stiffness Compliant Actuator and Its Error Compensation Method
Compliant actuators are more advantageous than stiff actuators in some circumstances, for example, unstructured environment robots and rehabilitation robots. Compliant actuators are more adaptive and safe. Constant stiffness compliant actuators have some
Shaobin Lan, Zhibin Song
doaj +1 more source
A 3D Human Neuron‐on‐Chip Platform to Monitor Neuronal Injury Responses
This study presents a novel 3D Neuron‐on‐Chip model that can maintain human PSC‐derived excitatory prefrontal cortex neurons in 3D hydrogels and can be used to monitor neuronal injury responses over time. Results show injury‐induced acute neuronal excitotoxicity, declining neuronal connectivity, and the activation of a neurodegenerative, SASP‐like ...
Ruiping Tang +16 more
wiley +1 more source
Variable Stiffness Structures Utilizing Pneumatic Artificial Muscles
Pneumatic artificial muscles (PAMs) can offer excellent force-to-weight ratios and act as shape-changing actuator under injecting the actuation fluid into their bladders. PAMs could be easily utilized for morphing structures due to their millimeter-scale
Ning Feng, Chang Yingli, Wang Jingze
doaj +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
Tomographic Printing in a Chip: A Versatile Platform for Biomimetic 3D Organ‐on‐Chip
A novel light‐based bioprinting approach, TVAM‐in‐a‐chip, enables rapid, contactless fabrication of biomimetic 3D organ‐on‐chip devices directly within preassembled microfluidic platforms. This strategy supports diverse materials, including cell‐laden resins, and eliminates post‐assembly steps.
Riccardo Rizzo +3 more
wiley +1 more source
Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno +16 more
wiley +1 more source
Anti-Disturbance Sliding Mode Control of a Novel Variable Stiffness Actuator for the Rehabilitation of Neurologically Disabled Patients. [PDF]
Mo L +6 more
europepmc +1 more source
Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen +5 more
wiley +1 more source

