Results 61 to 70 of about 4,239,690 (235)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Thermal conductivity of gas mixtures for polyurethane rigid foams [PDF]

, 2009
Mestrado em Engenharia QuímicaA temática do presente trabalho insere-se na procura de agentes expansores mais eficientes para espumas de poliuretano.
Varanda, Catarina Daniela Gonçalves Pinto
core  

Stability and Thermal Conductivity Characteristics of Nanofluids (H2O/CH3OH + NaCl + Al2O3 Nanoparticles) for CO2 Absorption Application [PDF]

, 2012
In this study, the nanofluids are produced by dispersing Al2O3 nanoparticles in the H2O/CH3OH binary mixtures using an ultrasonic equipment. Solid Sodium Chlorides (NaCl) with a fixed mass fraction are dissolved in the binary mixture for CO2 absorption ...
Pang, Changwei, Kang, Yong Tae
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Thermal properties of vesicular rhyolite [PDF]

, 1994
Thermal diffusivity of rhyolite melt and rhyolite foam (70–80% porosity) has been measured using the radial heat transfer method. Cylindrical samples (length 50–55 mm, diameter 22 mm) of rhyolite melt and foam have been derived by heating samples of ...
Bagdassarov, Nikolai, Dingwell, Donald B.   +1 more
core   +1 more source

Influence of variable fluid properties on mixed convective Darcy–Forchheimer flow relation over a surface with Soret and Dufour spectacle

Open Physics
The thermo-diffusion applications of nanofluid subject to variable thermal sources have been presented. The significance of Darcy–Forchheimer effects is attributed. The flow comprises the mixed convection and viscous dissipation effects. Furthermore, the
Li Shuguang, Khan Muhammad Ijaz, Ali Shahid, Ullah Khan Sami, Althobaiti Saja Abdulrahman, Khan Ilyas, Alqurashi Faris, Kchaou Mohamed   +7 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Thermal response testing through the chalk aquifer

, 2013
Thermal conductivity of the ground is an important parameter in the design of ground energy systems, which have an increasing role to play in providing renewable heat to the built environment.
Powrie, W., Powrie, W, Roberts, T, Loveridge, F, Holmes, G, Roberts, T., Holmes, G., Loveridge, F.   +7 more
core   +1 more source