Results 71 to 80 of about 33,614 (304)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Dimensioning of Boreholes for Geothermal Heat Pumps [PDF]

Acta Montanistica Slovaca, 2004
The paper deals with determination of borehole depths for geothermal heat pumps. Basic formulae are stated for heat convection in rocks. Software EED 2.0 was used for calculation of borehole depth depending on different entering parameters.
Ryška Jiøí
doaj  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Variable Thermal Conductivity on Compressible Boundary Layer Flow over a Circular Cylinder

, 2013
In this paper, variable thermal conductivity on heat transfer over a circular cylinder is presented. The concept of assuming constant thermal conductivity on materials is however not efficient.
Oyem, OA, Koriko, OK
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Measurement of Tissue Thermal Conductivity With Variable Thermal Dose During an Electrosurgical Joining Process

, 2017
Electrosurgical vessel joining is commonly performed in surgical procedures to maintain hemostasis. This process requires elevated temperature to denature the tissue and while compression is applied, the tissue can be joined together.
Samantha Kaonis, Che-Hao Yang, Wei Li, Roland K. Chen   +3 more
core   +1 more source

An unsteady squeezed flow of a tangent hyperbolic fluid over a sensor surface in the presence of variable thermal conductivity

Results in Physics, 2017
The paper explores the numerical study on squeezed flow of tangent hyperbolic fluid over a sensor surface with variable thermal conductivity. The governing equations are reassembling into ordinary non-linear differential equations by using suitable ...
K. Ganesh Kumar, B.J. Gireesha, M.R. Krishanamurthy, N.G. Rudraswamy   +3 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Investigation of double diffusion Cattaneo-Christov model in mixed convection flow by variable thickness surface

Results in Physics, 2017
This investigation examines the characteristics of nonlinear mixed convection flow by stretching sheet with variable thickness. Double diffusion Cattaneo-Christov heat flux model is implemented.
Tasawar Hayat, Zeenat Bashir, Sumaira Qayyum, Ahmed Alsaedi   +3 more
doaj   +1 more source