Results 21 to 30 of about 318,091 (221)

Temporal variability and statistics of the Strehl ratio in adaptive-optics images

, 2008
We have investigated the temporal variability and statistics of the "instantaneous" Strehl ratio. The observations were carried out with the 3.63-m AEOS telescope equipped with a high-order adaptive optics system. In this paper Strehl ratio is defined as
Born M., Box G. E. P., Cheng R. C. H., Goodman J. W., Green P. J., Julian C. Christou, Kenney J. F., L. William Bradford, Lewis C. Roberts, Press W. H., Ross S. M., Szymon Gladysz, Tyson R. K., Wall J. V.   +13 more
core   +1 more source

Precise Asymptotics for a Random Walker's Maximum [PDF]

, 2005
We consider a discrete time random walk in one dimension. At each time step the walker jumps by a random distance, independent from step to step, drawn from an arbitrary symmetric density function. We show that the expected positive maximum E[M_n] of the
Abramowitz M, Alain Comtet, Bertoin J, Blumen A, Coffman E G, Feller W, Gradshteyn I S, Hughes B, Kearney M J, Kearney M J, Koshland D E, Magnus W, Majumdar S N, Montroll E W, Morse P M, Petrov V V, Pollaczek F, Redner S, Satya N Majumdar, Spitzer F   +19 more
core   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

The distribution of the product of independent variance-gamma random variables

Journal of Mathematical Analysis and Applications
Let $X$ and $Y$ be independent variance-gamma random variables with zero location parameter; then the exact probability density function of the product $XY$ is derived. Some basic distributional properties are also derived, including formulas for the cumulative distribution function and the characteristic function, as well as asymptotic approximations ...
Robert E. Gaunt, Siqi Li
openaire   +2 more sources

Liquidity analysis and prediction in the processing industry by applying VG process: The case of the Czech Republic [PDF]

, 2017
This paper is devoted to liquidity analysis and prediction possibilities in the processing industry in the Czech Republic. The objective of this paper is to propose and apply pyramidal decomposition of the current liquidity ratio time series of the ...
Gurný, Petr, Richtarová, Dagmar, Čulík, Miroslav   +2 more
core   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Distribusi Invers Gamma pada Inferensi Bayesian [PDF]

, 2010
One of the methods which can be used in statistical inferences is Bayesian inference. It is combine sample distribution and prior distribution, that can be resulted posterior distribution.
Ispriyanti, D. (Dwi), Sugito, S. (Sugito)   +1 more
core  

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source