Results 101 to 110 of about 7,497,770 (317)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

On calculating estimates of stratified error-components models [PDF]

open access: yes
This note provides an AECM (alternating expectation conditional maximization) algorithm for calculating maximum-likelihood estimates of stratified error-components models.
Robert Phillips
core  

Sequential Tests for Variance Ratios and Components of Variance

open access: yesThe Annals of Mathematical Statistics, 1958
A general sequential sampling method is given for problems of comparing the variances of two or more normal populations in terms of ratios of variances. Sequential tests are given for a hypothesis specifying the ratio of two variances, including tests for variance components in the analysis of variance (Model II).
openaire   +3 more sources

Nonnegative estimation of variance components in unbalanced mixed models with two variance components

open access: yesJournal of Multivariate Analysis, 1992
AbstractAn unbalanced mixed linear model with two variance components is considered, one variance component (say σ12 ≥ 0) corresponding to a random effect (treatments) and a second variance component (say σ2 > 0) corresponding to the experimental errors.
Bimal K. Sinha   +2 more
openaire   +2 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Herdabilidades de parâmetros de curvas de crescimento não-lineares em zebuínos, no estado de Pernambuco Heritabilities of nonlinear growth curve parameters in zebu breeds, in Pernambuco State, Northeastern Brazil

open access: yesRevista Brasileira de Zootecnia, 2005
Objetivou-se estimar parâmetros genéticos e fenotípicos de curvas de crescimento de modelos não-lineares. Foram analisados dados de pesagem constantes no banco de dados de Controle de Desenvolvimento Ponderal da Associação Brasileira de Criadores de Zebu
Kleber Régis Santoro   +3 more
doaj   +1 more source

The variance of some common estimators and its components under nonresponse [PDF]

open access: yes
In most surveys, the risk of nonresponse is a factor taken into account at the planning stage. Commonly, resources are set aside for a follow-up procedure which aims at reducing the nonresponse rate.
Tångdahl, Sara
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Heterocedasticidade entre estados para produção de leite em vacas da raça Holandesa, usando métodos Bayesianos via amostrador de Gibbs An evaluation of heteroscedasticity of variances of milk yield of Holstein cattle in different states using Bayesian inference via Gibbs sampler

open access: yesRevista Brasileira de Zootecnia, 2006
Registros de produção de leite ajustados para 305 dias de lactação (PL305) em vacas da raça Holandesa que pariram entre 1980 e 1993 foram utilizados para investigar a existência de heterogeneidade de variância e a interação genótipo × ambiente.
Alencariano José da Silva Falcão   +4 more
doaj   +1 more source

Chemometric modelling to relate antioxidants, neutral lipid fatty acids and flavour components in chicken breast [PDF]

open access: yes, 2005
Relationships among quality factors in retailed free-range, corn-fed, organic, and conventional chicken breasts (9) were modeled using chemometric approaches.
Jahan, K.   +3 more
core  

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