Results 81 to 90 of about 817,120 (303)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Eigenvalue, variance, and cumulative variance of the 10 principle components. [PDF]

open access: yes, 2019
Eigenvalue, variance, and cumulative variance of the 10 principle components.
Eleni Healey (7513271)   +7 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Ratio of Variances in a Variance Components Model

open access: yesThe Annals of Mathematical Statistics, 1955
1. The general incomplete block variance components model. Suppose that yij for i = 1, * ,u, and j = 1, * ,b are independent and normal for given ti I., I tu with means E(yij I t) = nij(ti + bj) and v-ariance a2.
openaire   +2 more sources

Phenotypically standardized genetic variance components. [PDF]

open access: yes, 2019
Phenotypically standardized genetic variance components.
Stacey S. Cherny (120484)   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Eggshell Qualities as Indicative of Eggshell Strength for Layer Selection

open access: yesBrazilian Journal of Poultry Science
The study aimed at investigating which of four traits is the most representative of eggshell strength (destructive eggshell thickness measurement, eggshell weight, egg specific gravity, ultrasonic measurement of eggshell thickness) and could be used for ...
L Kibala   +4 more
doaj   +1 more source

Performance of Brazilian Companies: Year Effects, Line of Business and Individual Firms [PDF]

open access: yesBAR: Brazilian Administration Review, 2004
Performance varies. This simple statement conceals many intricacies of strategic management. Because performance varies among individual firms, researchers can explore factors that differentiate these firms and explain why some firms are consistently ...
Luiz Artur Ledur Brito   +1 more
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Confidence Intervals for Variance Components (II) [PDF]

open access: yesThe Egyptian Statistical Journal, 1982
Ken-Ming Husueh, Oskar Feichtinger
doaj   +1 more source

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