Results 101 to 110 of about 779,832 (257)

REHE: Fast variance components estimation for linear mixed models. [PDF]

Genet Epidemiol, 2021
Yue K, Ma J, Thornton T, Shojaie A.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Investigating the impact of non-additive genetic effects in the estimation of variance components and genomic predictions for heat tolerance and performance traits in crossbred and purebred pig populations. [PDF]

BMC Genom Data, 2023
de Oliveira LF, Brito LF, Marques DBD, da Silva DA, Lopes PS, Dos Santos CG, Johnson JS, Veroneze R.   +7 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Heritability and variance components of seed size in wild species: influences of breeding design and the number of genotypes tested. [PDF]

Heredity (Edinb), 2023
Larios E, Ramirez-Parada TH, Mazer SJ.
europepmc   +1 more source

Fiducial Limits for a Variance Component

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1963
SUMMARY The exact fiducial distribution is obtained for a variance component, and compared with a previous approximation.
openaire   +2 more sources

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

A link function approach to heterogeneous variance components

Genetics Selection Evolution, 1998
d'Arnoldi Caroline, Quaas Richard L, Foulley Jean-Louis   +2 more
doaj   +1 more source

Which method is optimal for estimating variance components and their variability in generalizability theory? evidence form a set of unified rules for bootstrap method. [PDF]

PLoS One, 2023
Li G.
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source