Results 101 to 110 of about 2,210,403 (291)

Likelihood inference for small variance components

open access: yes, 2015
The authors explore likelihood-based methods for making inferences about the components of variance in a general normal mixed linear model. In particular, they use local asymptotic approximations to construct confidence intervals for the components of ...
Stern, Steven E, Welsh, A. H.
core  

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

Ajustamento para heterogeneidade de variâncias para produção de leite e gordura entre rebanhos da raça Pardo-Suíça no Brasil Adjustment for heterogeneity of variance for milk and fat yield among herds of Brown Swiss in Brazil

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
Para verificar o efeito da inclusão das interações reprodutor x rebanho e reprodutor x rebanho-ano como fator de ajustamento da heterogeneidade de variância, registros de produção de leite e gordura foram estratificados, com base no desvio-padrão ...
R.S. Bueno   +6 more
doaj   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

Modelagem e estimação de parâmetros genéticos e fenotípicos para pesos do nascimento à seleção (378 dias) de machos Nelore Modeling and estimation of genetic parameters for weights from birth to selection age (378 Days) of Nellore males

open access: yesRevista Brasileira de Zootecnia, 2004
Parâmetros genéticos para pesos (17.942 observações), obtidos em intervalos de 60 dias, do nascimento ao momento da seleção (378 dias de idade), de 2.582 animais machos da raça Nelore, foram estimados em análises univariadas pelo método da máxima ...
Joslaine Noely dos Santos Gonçalves Cyrillo   +4 more
doaj   +1 more source

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason   +14 more
wiley   +1 more source

Robust Henderson III estimators of variance components in the nested error model [PDF]

open access: yes
Common methods for estimating variance components in Linear Mixed Models include Maximum Likelihood (ML) and Restricted Maximum Likelihood (REML). These methods are based on the strong assumption of multivariate normal distribution and it is well know ...
Betsabé Pérez   +2 more
core  

A Confidence Interval for Variance Components

open access: yesThe Annals of Mathematical Statistics, 1954
In this paper an approximate confidence interval is found for the expected value of the difference between two quantities which are independently distributed proportionally to $\chi^2$ variates. Three methods are used. The first is based on the work of Welch [13], [14] and Aspin [1], [2] on the generalized "Student's" problem, and involves neglecting ...
openaire   +2 more sources

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa   +8 more
wiley   +1 more source

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