Results 121 to 130 of about 7,252,224 (344)

Event‐to‐event variations in the isotopic composition of neon in solar energetic particle events [PDF]

, 1999
R. A. Leske, R. A. Mewaldt, C. M. S. Cohen, A. C. Cummings, E. C. Stone, M. E. Wiedenbeck, E. R. Christian, T. T. von Rosenvinge   +7 more
openalex   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Harmful Microalgae Exhibit Broad Environmental Adaptability in High‐Salinity Area Across the Dafengjiang River Estuary

Ecology and Evolution
Harmful algal blooms (HABs) often occur in estuaries due to their unique environmental heterogeneity, posing significant environmental and human health risks. However, there is limited understanding of the community composition and community‐level change
Jiongqing Huang, Huaxian Zhao, WeiJun Wang, Xinyi Qin, Pengbin Wang, Qinghua Hou, Qingxiang Chen, Gonglingxia Jiang, Ke Dong, Tao Jiang, Yang Pu, Nan Li   +11 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Difference-in-Differences with Variation in Treatment Timing

Journal of Econometrics, 2018
Andrew Goodman-Bacon
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Interannual synchronization of the North American summer monsoon and the North Atlantic tropical cyclone genesis frequency

Environmental Research Letters
Variations of the North American summer monsoon (NASM) and North Atlantic tropical cyclone (NATC) activities strongly influence climate anomalies in North America, with serious potential risk to life and property.
Jianzhou Luo, Jinwen Weng, Weijian Luo, Lei Wang   +3 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Bayesian modelling of inseparable space‐time variation in disease risk

, 2000
Leonhard Knorr‐Held
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source