Results 131 to 140 of about 9,552,128 (326)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Functional Genetic Variation in the Anti-Müllerian Hormone Pathway in Women With Polycystic Ovary Syndrome [PDF]

, 2019
Lidija K. Gorsic, Matthew Dapas, Richard S. Legro, M. Geoffrey Hayes, Margrit Urbanek   +4 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Interannual synchronization of the North American summer monsoon and the North Atlantic tropical cyclone genesis frequency

Environmental Research Letters
Variations of the North American summer monsoon (NASM) and North Atlantic tropical cyclone (NATC) activities strongly influence climate anomalies in North America, with serious potential risk to life and property.
Jianzhou Luo, Jinwen Weng, Weijian Luo, Lei Wang   +3 more
doaj   +1 more source

Transcriptional plasticity buffers genetic variation in zinc homeostasis [PDF]

, 2019
Alice Pita-Barbosa, Felipe Klein Ricachenevsky, Michael Wilson, Tania Dottorini, David E. Salt   +4 more
openalex   +1 more source

Somatic Variation [PDF]

Science, 1919
L J, Cole, J, Megeath
openaire   +2 more sources

Variation in Orbiviruses

Journal of General Virology, 1979
Introduction. The name orbiviruses was proposed by Borden et al. (1971) to describe a group of arthropod-borne viruses which, by their physico-chemical properties and characteristic appearance by electron microscopy, were sufficiently distinct to form a new taxonomic group.
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The EDGE–CALIFA Survey: Variations in the Molecular Gas Depletion Time in Local Galaxies [PDF]

, 2017
Dyas Utomo, Alberto D. Bolatto, TONY Wong, Eve C. Ostriker, Leo Blitz, Sebastián F. Sánchez, Dario Colombo, Adam K. Leroy, Yixian Cao, Helmut Dannerbauer, Rubén García Benito, Bernd Husemann, Veselina Kalinova, Rebecca C. Levy, Damian Mast, Erik Rosolowsky, Stuart N. Vogel   +16 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source