Results 11 to 20 of about 3,606,645 (224)
Total variation diminishing nonstandard finite difference schemes for conservation laws [PDF]
, 2009 Nonstandard finite difference schemes for conservation laws preserving the property of diminishing total variation of the solution are proposed. Computationally simple implicit schemes are derived by using nonlocal approximation of nonlinear terms ...
Anguelov, Roumen +2 more
core +1 more source
Variation diminishing property with b = 1 p = 3 k = 1.
, 2016 Variation diminishing property with b = 1 p = 3 k = 1.
Abdul Majeed (725054) +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Interpolatory and variation-diminishing properties of generalized B-splines
, 1984 SynopsisWe consider classes of functions satisfying certain simple criteria of sign and smoothness and a decomposition property. It is known that these properties are possessed by Chebysheffian B-splines and it is shown here that they are also possessed ...
S. L. Lee, T. N. T. Goodman
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Variation entropy: a continuous local generalization of the TVD property using entropy principles
, 2019 This paper presents the notion of a variation entropy. This concept is an entropy framework for the gradient of the solution of a conservation law instead of on the solution itself. It appears that all semi-norms are admissible variation entropies.
ten Eikelder, M.F.P. (author) +1 more
core +1 more source
Total variation diminishing schemes in optimal control of scalar conservation laws [PDF]
, 2017 In this paper, optimal control problems subject to a nonlinear scalar conservation law are studied. Such optimal control problems are challenging both at the continuous and at the discrete level since the control-to-state operator poses difficulties as ...
Hajian, Soheil +5 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source