Results 91 to 100 of about 18,872 (309)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
CONFIGURATIONAL FORCES IN STRUCTURAL AND CONTINUUM OPTIMISATION [PDF]
, 2008 This thesis deals with optimisation using the principles of continuum mechanics. Both shape and mesh optimisation will be covered. A unified approach will be introduced to obtain shape and mesh optimisation for hyperelastic, hyperelastodynamic and ...
Uthman, Zana, UTHMAN, Z
core
Primal and Dual Variational Formulation of a Frictional Contact Problem [PDF]
, 2016 International audienceThis paper represents a continuation of Barboteu et al. (Analysis of a contact problem with unilateral constraint and slip-dependent friction, Math Mech Sol, 2015).
Sofonea, Mircea +2 more
core +1 more source
A Tensor Variational Formulation of Gradient Energy Total Variation [PDF]
, 2015 We present a novel variational approach to a tensor-based total variation formulation which is called gradient energy total variation, GETV. We introduce the gradient energy tensor [6] into the GETV and show that the corresponding Euler-Lagrange (E-L) equation is a tensor-based partial differential equation of total variation type. Furthermore, we give
Freddie Åström +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Quasi-variational inequality formulation of the mixed equilibrium in multiclass routing games [PDF]
In the modeling of competition on networks it is usually assumed that users either behave following the Wardrop equilibrium or the Nash equilibrium concept.
SCRIMALI, Laura
core
A Variational Stereo Method for the Three-Dimensional Reconstruction of Ocean Waves [PDF]
, 2011 We develop a novel remote sensing technique for the observation of waves on the ocean surface. Our method infers the 3-D waveform and radiance of oceanic sea states via a variational stereo imagery formulation.
Yezzi, Anthony +7 more
core +2 more sources
Analysis of electro-viscoelastic antiplane contact problem with total slip rate dependent friction
Electronic Journal of Differential Equations, 2009 We consider a mathematical model which describes the antiplane shear deformation of a cylinder in frictional contact with a rigid foundation. The contact is bilateral and is modelled with a total slip rate dependent friction law.
Mohamed Dalah
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source